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Down-regulation of A-FABP predicts non-muscle invasive bladder cancer progression: investigation with a long term clinical follow-up

机译：A-FABP的下调可预测非肌肉浸润性膀胱癌的进展：长期临床随访研究

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摘要

BackgroundNon-muscle invasive bladder cancers (NMIBC: pTa, pT1) are characterised by a high risk of recurrence and/or progression. Identification of prognostic markers is needed to improve both diagnosis and management of the disease. The aim of this study was to analyse the expression of A-FABP (adipocyte-fatty acid binding protein) and to evaluate its prognostic value in bladder cancer with a long term clinical follow-up.

机译：背景非肌肉浸润性膀胱癌（NMIBC：pTa，pT1）的特点是复发和/或进展的风险很高。需要鉴定预后标志物以改善疾病的诊断和管理。这项研究的目的是分析A-FABP（脂肪细胞-脂肪酸结合蛋白）的表达，并通过长期临床随访评估其在膀胱癌中的预后价值。

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期刊名称 BMC Cancer
作者
Christel Mathis; Isabelle Lascombe; Franck Monnien; Hugues Bittard; François Kleinclauss; Isabelle Bedgedjian; Sylvie Fauconnet; Séverine Valmary-Degano;
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作者单位

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年(卷),期 2018(18),-1
年度 2018
页码 1239
总页数 13
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Bladder cancer A-FABP FABP4 Adipocyte-fatty acid binding protein Prognostic marker;

机译：膀胱癌;A-FABP;FABP4;脂肪细胞-脂肪酸结合蛋白;预后指标;

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专利

1. Down-regulation of A-FABP predicts non-muscle invasive bladder cancer progression: investigation with a long term clinical follow-up [J] . Christel Mathis, Isabelle Lascombe, Franck Monnien, BMC Cancer . 2018,第1期

机译：A-FABP的下调预测非肌肉侵袭性膀胱癌进展：与长期临床随访进行调查
2. miR-221/222 cluster expression improves clinical stratification of non-muscle invasive bladder cancer (TaT1) patients' risk for short-term relapse and progression [J] . Tsikrika Foteini D., Avgeris Margaritis, Levis Panagiotis K., Genes, Chromosomes and Cancer . 2018,第3期

机译：miR-221/222簇表达改善了非肌肉侵袭性膀胱癌（TAT1）患者短期复发和进展风险的临床分层
3. Long term follow-up in patients with initially diagnosed low grade Ta non-muscle invasive bladder tumors: tumor recurrence and worsening progression [J] . Hiroaki Kobayashi, Eiji Kikuchi, Shuji Mikami, BMC Urology . 2014,第1期

机译：最初诊断为低度Ta非肌肉浸润性膀胱肿瘤的患者的长期随访：肿瘤复发和病情恶化
4. Improved temperature monitoring and treatment planning for loco-regional hyperthermia treatments of Non-Muscle Invasive Bladder Cancer (NMIBC) [C] . G. Schooneveldt, H.P. Kok, E.D. Geijsen World Congress on Medical Physics and Biomedical Engineering . 2015

机译：改善对非肌肉侵袭性膀胱癌（NMIBC）的基因群体热疗治疗的温度监测和治疗计划
5. Understanding treatment-related symptoms, symptom management techniques, and symptom management self-efficacy in a sample of non-muscle invasive bladder cancer patients [D] . Hinojosa-Lindsey, Marilyn 2010

机译：了解非肌肉浸润性膀胱癌患者样本中与治疗相关的症状，症状管理技术和症状管理自我效能
6. Long term follow-up in patients with initially diagnosed low grade Ta non-muscle invasive bladder tumors: tumor recurrence and worsening progression [O] . Hiroaki Kobayashi, Eiji Kikuchi, Shuji Mikami, 2014

机译：最初诊断为低度Ta非肌肉浸润性膀胱肿瘤的患者的长期随访：肿瘤复发和病情恶化
7. Long term follow-up in patients with initially diagnosed low grade Ta non-muscle invasive bladder tumors: tumor recurrence and worsening progression [O] . 2014

机译：最初诊断为低度Ta非肌肉浸润性膀胱肿瘤的患者的长期随访：肿瘤复发和病情恶化

Down-regulation of A-FABP predicts non-muscle invasive bladder cancer progression: investigation with a long term clinical follow-up

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