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Endovascular management of ruptured distal posterior inferior cerebellar artery aneurysms

机译:小脑后下动脉远端破裂的血管内处理

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摘要

Distal posterior inferior cerebellar artery (PICA) aneurysm is a kind of rare intracranial aneurysm with controversial evidence in managements. The main purposes of this research are to study the safety and effectiveness of parent artery occlusion (PAO) compared with selective aneurysm coiling (SAC) as well as figure out factors that affect the outcomes.All characteristics of patients that diagnosed with ruptured distal PICA aneurysm and treated with endovascular management in our hospital from July 2009 to February 2016 were retrospectively collected. Details include complete occlusion rate, procedure-related complications and Modified Rankin Scale (mRS) of 31 months (mean) follow-up.Total 36 patients finally met the criterions and were included in the present study. New imaging infarction was observed in 12 (33.33%) patients. And 10 of them showed no apparent neurological dysfunctions after 34 months (mean) follow-up; 1 remained coma status since the symptom onset; and 1 patient died. 27 (75%) patients got a mRS ≤ 2 at the discharge while 20 (86.96%) patients with 3-year follow-up after the operation. There is no significant difference between patients treated with SAC and PAO in both complications and functional recovery in 3-years follow-up period. Hunt&Hess classification (H&H), age, and hydrocephalus are risk factors for functional recovery at discharge.PAO is safe and efficient in the management of distal PICA aneurysms while complications and outcomes are similar with SAC. H&H, age, and hydrocephalus are predicting factors for the mRS at discharge. Further prospective study is still needed to confirm the results of present study.
机译:小脑后下动脉(PICA)远端动脉瘤是一种罕见的颅内动脉瘤,在治疗中存在有争议的证据。这项研究的主要目的是研究与选择性动脉瘤卷曲术(SAC)相比,亲代动脉闭塞(PAO)的安全性和有效性,并找出影响预后的因素。诊断为远端PICA动脉瘤破裂的患者的所有特征回顾性收集2009年7月至2016年2月在我院接受血管内治疗的患者。详细信息包括完全阻塞率,与手术相关的并发症和31个月(平均)随访的改良Rankin量表(mRS)。总共36例患者最终符合标准,被纳入本研究。在12名(33.33%)患者中观察到新的影像学梗死。其中10例在随访34个月(平均)后未显示出明显的神经功能障碍。自症状发作以来1例保持昏迷状态; 1例患者死亡。 27例(75%)患者出院时mRS≤2,而20例(86.96%)患者术后3年随访。在3年的随访期内,SAC和PAO治疗的患者在并发症和功能恢复方面均无显着差异。 Hunt&Hess分类(H&H),年龄和脑积水是出院时功能恢复的危险因素.PAO安全有效地治疗了远端PICA动脉瘤,而并发症和结局与SAC相似。 H&H,年龄和脑积水是出院时mRS的预测因素。仍需要进一步的前瞻性研究来证实本研究的结果。

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