Effect of Netrin-1 Anti-Inflammatory Factor on Acute Lung Injury in Sepsis Rats

机译：Netrin-1抗炎因子对脓毒症大鼠急性肺损伤的影响

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BackgroundsAcute lung injury (ALI) often occurs early and seriously in the progress of sepsis. Netrin-1 is demonstrated to be an effective anti-inflammatory agent. However, whether netrin-1 can relieve sepsis-induced ALI remains unknown.

机译：背景急性肺损伤（ALI）通常在脓毒症的进展过程中尽早且严重地发生。 Netrin-1被证明是有效的抗炎药。但是，netrin-1是否能缓解败血症诱导的ALI尚不清楚。

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期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Jisong Liu; Juan Du; Xiu Cheng; Xiangzhou Zhang; Yong Li; Xiujun Fu; Xulin Chen;
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作者单位

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年(卷),期 2019(25),-1
年度 2019
页码 7928–7935
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
Acute Lung Injury Exosomes Sepsis;

机译：急性肺损伤;外来体;败血症;

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专利

1. NLRP3 gene silencing ameliorates phosgene-induced acute lung injury in rats by inhibiting NLRP3 inflammasome and proinflammatory factors, but not anti-inflammatory factors [J] . Dai-Kun He, Ning Xu, Yi-Ru Shao, The Journal of toxicological sciences . 2020,第10期

机译：NLRP3基因沉默通过抑制NLRP3炎症和促炎因子，但不是抗炎因素，改善了大鼠的光气诱导的急性肺损伤。
2. Astilbin alleviates sepsis-induced acute lung injury by inhibiting the expression of macrophage inhibitory factor in rats [J] . Zhang Hong-bo, Sun Li-chao, Zhi Li-da, Archives of pharmacal research . 2017,第10期

机译：Astilbin通过抑制大鼠巨噬细胞抑制因子的表达来减轻败血症诱导的急性肺损伤
3. Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury [J] . Kral-Pointner J. B., Schrottmaier W. C., Horvath V., Limnology and oceanography, methods . 2017,第8期

机译：骨髓，但不是上皮组织因子在酸吸入诱导的急性肺损伤中发挥保护性抗炎作用
4. Anti-inflammatory biocompatible dexamethasone-loaded porous microparticles for acute lung injury [C] . Dahee Jeong, Iljea Lee, Yerang Kim, Society for biomaterials annual meeting and exposition . 2013

机译：抗炎生物相容性地塞米松负载多孔微粒治疗急性肺损伤
5. Hsp-90 inhibitors in sepsis and sepsis-induced acute lung injury [D] . Chatterjee, Anuran 2007

机译：Hsp-90抑制剂在败血症和败血症诱导的急性肺损伤中的作用
6. Alleviation of Acute Lung Injury in Rats with Sepsis by Resveratrol via the Phosphatidylinositol 3-Kinase/Nuclear Factor-Erythroid 2 Related Factor 2/Heme Oxygenase-1 (PI3K/Nrf2/HO-1) Pathway [O] . Yu Wang, Xiaofeng Wang, Lichun Zhang, 1923

机译：白藜芦醇通过磷脂酰肌醇3-激酶/核因子-类胡萝卜素2相关因子2 /血红素加氧酶-1（PI3K / Nrf2 / HO-1）途径减轻白藜芦醇对脓毒症大鼠的急性肺损伤
7. Tumor necrosis factor-alpha blockade prevents neutrophil CD18 receptor upregulation and attenuates acute lung injury in porcine sepsis without inhibition of neutrophil oxygen radical generation. [O] . Windsor, A C, Walsh, C J, Mullen, P G, 1993

机译：肿瘤坏死因子-α阻断剂可预防猪败血症中的中性粒细胞CD18受体上调并减轻急性肺损伤，而不会抑制中性粒细胞氧自由基的产生。
8. Mechanism of Tissue Remodeling in Sepsis-Induced Acute Lung Injury [R] . Roman, J. 2006

机译：脓毒症致急性肺损伤组织重塑机制的研究

Effect of Netrin-1 Anti-Inflammatory Factor on Acute Lung Injury in Sepsis Rats

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