Proof-of-principle investigation of an algorithmic model of adenosine-mediated angiogenesis

机译：腺苷介导的血管生成算法模型的原理验证研究

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BackgroundWe investigated an algorithmic approach to modelling angiogenesis controlled by vascular endothelial growth factor (VEGF), the anti-angiogenic soluble VEGF receptor 1 (sVEGFR-1) and adenosine (Ado). We explored its feasibility to test angiogenesis-relevant hypotheses. We illustrated its potential to investigate the role of Ado as an angiogenesis modulator by enhancing VEGF activity and antagonizing sVEGFR-1.

机译：背景我们研究了一种通过血管内皮生长因子（VEGF），抗血管生成可溶性VEGF受体1（sVEGFR-1）和腺苷（Ado）控制血管生成的算法方法。我们探索了其测试与血管生成相关的假设的可行性。我们阐明了其通过增强VEGF活性和拮抗sVEGFR-1来研究Ado作为血管生成调节剂的作用的潜力。

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期刊名称 Theoretical Biology Medical Modelling
作者
Francisco Azuaje; Frédérique Léonard; Magali Rolland-Turner; Yvan Devaux; Daniel R Wagner;
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年(卷),期 2011(8),-1
年度 2011
页码 7
总页数 20
原文格式 PDF
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中图分类生物学;
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机译：腺苷介导的血管生成算法模型的原理验证研究
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7. Proof-of-principle investigation of an algorithmic model of adenosine-mediated angiogenesis [O] . Francisco Azuaje, Frédérique Léonard, Magali Rolland-Turner, 2011

机译：腺苷介导的血管生成算法模型的原理验证研究

Proof-of-principle investigation of an algorithmic model of adenosine-mediated angiogenesis

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