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Dosimetry of oblique tangential photon beams calculated by superposition/convolution algorithms: a Monte Carlo evaluation

机译:叠加/卷积算法计算的斜切向光子束剂量学:蒙特卡洛评估

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摘要

Although there are many works on evaluating dose calculations of the anisotropic analytical algorithm (AAA) using various homogeneous and heterogeneous phantoms, related work concerning dosimetry due to tangential photon beam is lacking. In this study, dosimetry predicted by the AAA and collapsed cone convolution (CCC) algorithm was evaluated using the tangential photon beam and phantom geometry. The photon beams of 6 and 15 MV with field sizes of 4×4 (or 7×7), 10×10 and 20×20cm2, produced by a Varian 21 EX linear accelerator, were used to test performances of the AAA and CCC using Monte Carlo (MC) simulation (EGSnrc‐based code) as a benchmark. Horizontal dose profiles at different depths, phantom skin profiles (i.e., vertical dose profiles at a distance of 2 mm from the phantom lateral surface), gamma dose distributions, and dose‐volume histograms (DVHs) of skin slab were determined. For dose profiles at different depths, the CCC agreed better with doses in the air‐phantom region, while both the AAA and CCC agreed well with doses in the penumbra region, when compared to the MC. Gamma evaluations between the AAA/CCC and MC showed that deviations of 2D dose distribution occurred in both beam edges in the phantom and air‐phantom interface. Moreover, the gamma dose deviation is less significant in the air‐phantom interface than the penumbra. DVHs of skin slab showed that both the AAA and CCC underestimated the width of the dose drop‐off region for both the 6 and 15MV photon beams. When the gantry angle was 0°, it was found that both the AAA and CCC overestimated doses in the phantom skin profiles compared to the MC, with various photon beam energies and field sizes. The mean dose differences with doses normalized to the prescription point for the AAA and CCC were respectively:7.6%±2.6% and 2.1%±1.3% for a 10×10cm2 field, 6 MV; 16.3%±2.1% and 6.7%±2.1% for a 20×20cm2 field, 6 MV; 5.5%±1.2% and 1.7%±1.4% for a 10×10cm2, 15 MV; 18.0%±1.3% and 8.3%±1.8% for a 20×20cm2, 15 MV. However, underestimations of doses in the phantom skin profile were found with small fields of 4×4 and 7×7cm2 for the 6 and 15 MV photon beams, respectively, when the gantry was turned 5° anticlockwise. As surface dose with tangential photon beam geometry is important in some radiation treatment sites such as breast, chest wall and sarcoma, it is found that neither of the treatment planning system algorithms can predict the dose well at depths shallower than 2 mm. The dosimetry data and beam and phantom geometry in this study provide a better knowledge of a dose calculation algorithm in tangential‐like irradiation.PACS numbers: 87.55.‐x, 87.53.Bn, 87.55.K‐, 87.55.kh, 87.56.jf
机译:尽管有许多关于使用各种同质和异质体模评估各向异性分析算法(AAA)的剂量计算的工作,但由于切向光子束而导致的与剂量学有关的相关工作仍然缺乏。在这项研究中,使用切向光子束和幻影几何来评估由AAA和塌陷锥卷积(CCC)算法预测的剂量。 6和15 MV的光子束,其场大小为 4 × 4 (或 7 × 7 ), 10 × 10 20 × 20 cm 2 ,由使用Varian 21 EX线性加速器,以蒙特卡罗(MC)仿真(基于EGSnrc的代码)为基准,测试AAA和CCC的性能。确定了不同深度的水平剂量分布,幻影皮肤分布(即距幻影侧面2mm处的垂直剂量分布),伽马剂量分布以及皮肤平板的剂量体积直方图(DVH)。对于不同深度的剂量分布,与MC相比,CCC与空气幻影区域的剂量吻合得更好,而AAA和CCC与半影区域的剂量吻合得更好。 AAA / CCC和MC之间的Gamma评估表明,在幻像和空气-幻像界面的两个光束边缘都发生了二维剂量分布的偏差。此外,在空气-幻象界面中,γ剂量偏差不如半影中重要。皮肤平板的DVH显示AAA和CCC均低估了6MV和15MV光子束的剂量下降区域的宽度。当机架角度为0°时,发现与MC相比,幻影皮肤轮廓中的AAA和CCC都高估了剂量,并且具有各种光子束能量和视场大小。平均剂量差异与针对AAA和CCC的处方点标准化的剂量分别为: 7.6 ± 2.6 2.1 ± 1.3 10 < mo>× 10 cm 2 字段,6 MV; 16.3 < mo>% ± 2.1 6.7 ± 2.1 用于 20 × 20 < / mo> cm 2 字段,6 MV; 5.5 < mo>% ± 1.2 1.7 ± 1.4 用于 10 × 10 < / mo> cm 2 ,15 MV; 18.0 < mo>% ± 1.3 8.3 ± 1.8 用于 20 × 20 < / mo> cm 2 ,15 MV。然而,在 4 × 4 7 × 7 cm 2 当将机架逆时针旋转5°时,分别产生了6和15 MV光子束。由于具有切线光子束几何形状的表面剂量在某些放射线治疗部位(例如乳房,胸壁和肉瘤)中很重要,因此发现,任何治疗计划系统算法都无法在小于2 mm的深度很好地预测剂量。这项研究中的剂量学数据以及射束和体模的几何形状为切向照射中的剂量计算算法提供了更好的知识.PACS编号:87.55.-x,87.53.Bn,87.55.K-,87.55.kh,87.56.jf

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