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Proton dose distribution measurements using a MOSFET detector with a simple dose‐weighted correction method for LET effects

机译:使用MOSFET检测器的质子剂量分布测量以及用于LET效应的简单剂量加权校正方法

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摘要

We experimentally evaluated the proton beam dose reproducibility, sensitivity, angular dependence and depth‐dose relationships for a new Metal Oxide Semiconductor Field Effect Transistor (MOSFET) detector. The detector was fabricated with a thinner oxide layer and was operated at high‐bias voltages. In order to accurately measure dose distributions, we developed a practical method for correcting the MOSFET response to proton beams. The detector was tested by examining lateral dose profiles formed by protons passing through an L‐shaped bolus. The dose reproducibility, angular dependence and depth‐dose response were evaluated using a 190 MeV proton beam. Depth‐output curves produced using the MOSFET detectors were compared with results obtained using an ionization chamber (IC). Since accurate measurements of proton dose distribution require correction for LET effects, we developed a simple dose‐weighted correction method. The correction factors were determined as a function of proton penetration depth, or residual range. The residual proton range at each measurement point was calculated using the pencil beam algorithm. Lateral measurements in a phantom were obtained for pristine and SOBP beams. The reproducibility of the MOSFET detector was within 2%, and the angular dependence was less than 9%. The detector exhibited a good response at the Bragg peak (0.74 relative to the IC detector). For dose distributions resulting from protons passing through an L‐shaped bolus, the corrected MOSFET dose agreed well with the IC results. Absolute proton dosimetry can be performed using MOSFET detectors to a precision of about 3% (1 sigma). A thinner oxide layer thickness improved the LET in proton dosimetry. By employing correction methods for LET dependence, it is possible to measure absolute proton dose using MOSFET detectors.PACS number: 87.56.‐v
机译:我们通过实验评估了新型金属氧化物半导体场效应晶体管(MOSFET)检测器的质子束剂量重现性,灵敏度,角度依赖性和深度剂量关系。检测器由较薄的氧化层制成,并在高偏置电压下运行。为了准确地测量剂量分布,我们开发了一种实用的方法来校正MOSFET对质子束的响应。通过检查质子穿过L形弹丸形成的侧向剂量分布对检测器进行了测试。使用190 MeV质子束评估了剂量再现性,角度依赖性和深度剂量响应。将使用MOSFET检测器产生的深度输出曲线与使用电离室(IC)获得的结果进行比较。由于准确测量质子剂量分布需要校正LET效应,因此我们开发了一种简单的剂量加权校正方法。确定校正因子是质子穿透深度或残余范围的函数。使用铅笔束算法计算每个测量点的残留质子范围。对于原始光束和SOBP光束,在幻影中获得了横向测量值。 MOSFET检测器的重现性在2%以内,角度依赖性小于9%。该检测器在布拉格峰(相对于IC检测器为0.74)处表现出良好的响应。对于质子通过L形推注产生的剂量分布,校正后的MOSFET剂量与IC结果非常吻合。可以使用MOSFET检测器执行绝对质子剂量测定,精度约为3%(1 sigma)。较薄的氧化物层厚度改善了质子剂量法中的LET。通过采用LET依赖性校正方法,可以使用MOSFET检测器测量绝对质子剂量.PACS编号:87.56.-v

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