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Leptin Locally Synthesized in Carotid Atherosclerotic Plaques Could Be Associated With Lesion Instability and Cerebral Emboli

机译：瘦素在颈动脉粥样硬化斑块中局部合成可能与病灶不稳定和脑栓塞有关

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摘要

BackgroundUnstable carotid plaques cause cerebral emboli. Leptin promotes atherosclerosis and vessel wall remodeling. We hypothesized that carotid atherosclerotic lesion instability is associated with local leptin synthesis.

机译：背景不稳定的颈动脉斑块会引起脑栓塞。瘦素促进动脉粥样硬化和血管壁重塑。我们假设颈动脉粥样硬化病变的不稳定性与局部瘦素的合成有关。

著录项

期刊名称 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
作者
Jacob Schneiderman; Katrin Schaefer; Frank D. Kolodgie; Naphtali Savion; Shlomo Kotev-Emeth; Rima Dardik; Amos J. Simon; Moshe Halak; Clara Pariente; Isaac Engelberg; Stavros Konstantinides; Renu Virmani;
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作者单位

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年(卷),期 2012(1),5
年度 2012
页码 e001727
总页数 11
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
atherosclerosis leptin macrophages smooth muscle cells tumor necrosis factor-α;

机译：动脉粥样硬化;瘦素;巨噬细胞;平滑肌细胞;肿瘤坏死因子-α;

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专利

1. Leptin Locally Synthesized in Carotid Atherosclerotic Plaques Could Be Associated With Lesion Instability and Cerebral Emboli [J] . Amos J. Simon, Clara Pariente, Frank D. Kolodgie, Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease . 2012,第1期

机译：瘦素在颈动脉粥样硬化斑块中局部合成可能与病灶不稳定和脑栓塞有关
2. Cerebral Hyperperfusion after Revascularization Inhibits Development of Cerebral Ischemic Lesions Due to Artery-to-Artery Emboli during Carotid Exposure in Endarterectomy for Patients with Preoperative Cerebral Hemodynamic Insufficiency: Revisiting the “Impaired Clearance of Emboli” Concept [J] . Kentaro Fujimoto, Yoshiyasu Matsumoto, Kohki Oikawa, International Journal of Molecular Sciences . 2016,第8期

机译：血运重建后的脑过度灌注抑制术前脑血流动力学功能不全的患者在颈动脉内膜切除术中颈动脉暴露过程中因动脉间栓子引起的脑缺血性病变的发展：再次探讨“栓子清除率受损”的概念
3. Carotid atherosclerotic plaque instability and cognition determined by ultrasound-measured plaque strain in asymptomatic patients with significant stenosis [J] . Dempsey Robert J., Varghese Tomy, Jackson Daren C., Journal of neurosurgery. . 2018,第1期

机译：颈动脉粥样硬化斑块稳定性和认知通过明显狭窄的无症状患者中的超声测量斑块菌株确定
4. Plaque instability in human coronary atherosclerotic lesions: roles of oxidized LDL and neutrophils [C] . Makiko Ueda, Shoichi Ehara, Yoshiki Kobayashi International Symposium on Atherosclerosis . 2004

机译：人类冠状动脉粥样硬化病变中的斑块不稳定：氧化LDL和中性粒细胞的作用
5. Associations Between Magnetic Resonance Imaging Detected Intraplaque Hemorrhage and Carotid Artery Atherosclerotic Plaque Components in Mild to Severe Stenotic Non-surgical Patients [D] . Zhang, Bowen . 2019

机译：磁共振成像检测到肿瘤发血和颈动脉动脉粥样硬化斑纹斑块组分在轻度至严重狭窄非外科患者中的关联。
6. Cerebral Hyperperfusion after Revascularization Inhibits Development of Cerebral Ischemic Lesions Due to Artery-to-Artery Emboli during Carotid Exposure in Endarterectomy for Patients with Preoperative Cerebral Hemodynamic Insufficiency: Revisiting the Impaired Clearance of Emboli Concept [O] . Kentaro Fujimoto, Yoshiyasu Matsumoto, Kohki Oikawa, 2016

机译：血运重建后的脑过度灌注抑制术前脑血流动力学功能不全的患者在颈动脉内膜切除术中颈动脉暴露过程中因动脉间栓塞而引起的脑缺血病变的发展：重新探讨栓塞清除率受损的概念
7. Leptin Locally Synthesized in Carotid Atherosclerotic Plaques Could Be Associated With Lesion Instability and Cerebral Emboli [O] . Jacob Schneiderman, Katrin Schaefer, Frank D. Kolodgie, 2012

机译：在颈动脉粥样硬化斑块中局部合成的Leptin可能与病变不稳定和脑栓塞有关

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