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Development of real‐time motion verification system using in‐room optical images for respiratory‐gated radiotherapy

机译:使用室内光学图像开发实时运动验证系统用于呼吸门控放射治疗

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摘要

Phase‐based respiratory‐gated radiotherapy relies on the reproducibility of patient breathing during the treatment. To monitor the positional reproducibility of patient breathing against a 4D CT simulation, we developed a real‐time motion verification system (RMVS) using an optical tracking technology. The system in the treatment room was integrated with a real‐time position management system. To test the system, an anthropomorphic phantom that was mounted on a motion platform moved on a programmed breathing pattern and then underwent a 4D CT simulation with RPM. The phase‐resolved anterior surface lines were extracted from the 4D CT data to constitute 4D reference lines. In the treatment room, three infrared reflective markers were attached on the superior, middle, and inferior parts of the phantom along with the body midline and then RMVS could track those markers using an optical camera system. The real‐time phase information extracted from RPM was delivered to RMVS via in‐house network software. Thus, the real‐time anterior‐posterior positions of the markers were simultaneously compared with the 4D reference lines. The technical feasibility of RMVS was evaluated by repeating the above procedure under several scenarios such as ideal case (with identical motion parameters between simulation and treatment), cycle change, baseline shift, displacement change, and breathing type changes (abdominal or chest breathing). The system capability for operating under irregular breathing was also investigated using real patient data. The evaluation results showed that RMVS has a competence to detect phase‐matching errors between patient's motion during the treatment and 4D CT simulation. Thus, we concluded that RMVS could be used as an online quality assurance tool for phase‐based gating treatments.PACS number: 87.55.Qr
机译:基于阶段的呼吸门放射疗法依赖于治疗过程中患者呼吸的可重复性。为了通过4D CT模拟监测患者呼吸的位置可再现性,我们开发了使用光学跟踪技术的实时运动验证系统(RMVS)。治疗室中的系统与实时位置管理系统集成在一起。为了测试该系统,安装在运动平台上的拟人化体模以编程的呼吸模式移动,然后通过RPM进行4D CT仿真。从4D CT数据中提取相分辨的前表面线,以构成4D参考线。在治疗室中,将三个红外反射标记与人体中线一起附着在体模的上部,中部和下部,然后RMVS可以使用光学摄像系统跟踪这些标记。从RPM提取的实时阶段信息已通过内部网络软件传递到RMVS。因此,将标记的实时前后位置同时与4D参考线进行了比较。通过在理想情况下(模拟和治疗之间具有相同的运动参数),周期变化,基线偏移,位移变化和呼吸类型变化(腹部或胸部呼吸)等几种情况下重复上述过程,评估了RMVS的技术可行性。还使用真实的患者数据调查了系统在不规则呼吸下的操作能力。评估结果表明,RMVS具有检测治疗过程中患者运动与4D CT模拟之间的相位匹配误差的能力。因此,我们得出结论,RMVS可以用作基于相位的门控治疗的在线质量保证工具.PACS编号:87.55.Qr

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