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A two‐point scheme for optimal breast IMRT treatment planning

机译:最佳的乳房IMRT治疗计划的两点计划

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摘要

We propose an approach to determining optimal beam weights in breast/chest wall IMRT treatment plans. The goal is to decrease breathing effect and to maximize skin dose if the skin is included in the target or, otherwise, to minimize the skin dose. Two points in the target are utilized to calculate the optimal weights. The optimal plan (i.e., the plan with optimal beam weights) consists of high energy unblocked beams, low energy unblocked beams, and IMRT beams. Six breast and five chest wall cases were retrospectively planned with this scheme in Eclipse, including one breast case where CTV was contoured by the physician. Compared with 3D CRT plans composed of unblocked and field‐in‐field beams, the optimal plans demonstrated comparable or better dose uniformity, homogeneity, and conformity to the target, especially at beam junction when supraclavicular nodes are involved. Compared with nonoptimal plans (i.e., plans with nonoptimized weights), the optimal plans had better dose distributions at shallow depths close to the skin, especially in cases where breathing effect was taken into account. This was verified with experiments using a MapCHECK device attached to a motion simulation table (to mimic motion caused by breathing).PACS number: 87.55 de
机译:我们提出一种确定乳房/胸壁IMRT治疗计划中最佳束重的方法。目标是如果目标中包括皮肤,则降低呼吸效果并最大化皮肤剂量,否则,则最小化皮肤剂量。目标中的两个点用于计算最佳权重。最佳计划(即具有最佳波束权重的计划)包括高能无阻塞波束,低能无阻塞波束和IMRT波束。在Eclipse中使用该方案回顾性地计划了6例乳房和5例胸壁病例,其中1例由医生绘制了CTV轮廓的乳房病例。与由畅通无阻的光束和现场光束组成的3D CRT计划相比,最佳计划显示出可比或更好的剂量均匀性,均匀性和与目标的一致性,特别是在涉及锁骨上淋巴结的光束交界处。与非最佳计划(即权重未优化的计划)相比,最佳计划在靠近皮肤的较浅深度具有更好的剂量分布,尤其是在考虑呼吸效果的情况下。使用附在运动模拟表上的MapCHECK装置进行的实验验证了这一点(模拟呼吸引起的运动)。PACS编号:87.55 de

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