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Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010–2011 influenza season: high prevalence of mutations at antigenic sites

机译：2010–2011年流感季节安大略省季节性甲型流感病毒（H3N2）的遗传特征：抗原位点的突变率很高

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摘要

BackgroundThe direct effect of antigenic site mutations in influenza viruses on antigenic drift and vaccine effectiveness is poorly understood.

机译：背景流感病毒中抗原位点突变对抗原漂移和疫苗效力的直接影响了解甚少。

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期刊名称 Influenza and Other Respiratory Viruses
作者
AliReza Eshaghi; Venkata R Duvvuri; Aimin Li; Samir N Patel; Nathalie Bastien; Yan Li; Donald E Low; Jonathan B Gubbay;
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作者单位

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年(卷),期 2014(8),2
年度 2014
页码 250–257
总页数 8
原文格式 PDF
正文语种
中图分类病毒传染病;人体病毒学（致病病毒）;病毒（滤过性病毒）;
关键词
Antigenic site mutations genetic and antigenic characterization phylogenetic analysis positive selection analysis seasonal influenza A (H3N2) virus;

机译：抗原位点突变;遗传和抗原特性;系统发育分析;阳性选择分析;季节性甲型流感（H3N2）病毒;

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专利

1. Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010-2011 influenza season: High prevalence of mutations at antigenic sites [J] . EshaghiA., DuvvuriV.R., LiA., Influenza and other respiratory viruses. . 2014,第2期

机译：在2010-2011年流感季节期间，安大略省季节性甲型H3N2流感病毒的遗传特征：抗原位点的突变率很高
2. Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010–2011 influenza season: high prevalence of mutations at antigenic sites [J] . Aimin Li, AliReza Eshaghi, Donald E. Low, Influenza and other respiratory viruses. . 2014,第2期

机译：2010–2011年流感季节期间安大略省季节性甲型流感病毒（H3N2）的遗传特征：抗原位点的突变率很高
3. Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: Basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 Northern Hemisphere season [J] . Barr Ian G., McCauley John, Cox Nancy, Vaccine . 2010,第5期

机译：季节性甲型（H1N1），甲型（H3N2）和乙型流感病毒的流行病学，抗原学和遗传学特征：WHO关于在2009-2010年北半球季节使用的流感疫苗组成建议的依据
4. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from endemic viruses [C] . Daniela Rajao, Phillip Gauger, Tavis Anderson, Annual^Meeting of the American^Association^of^Swine^Veterinarians. . 2016

机译：新型重新排列的人样H3N2和H3N1流感在猪中检测到的病毒是毒性的，抗原与地方病毒不同
5. Effect of antigenic site mutations on the binding specificity of an anti-hemagglutinin antibody to H3N2 influenza virus isolates. [D] . Hagembe, Juliana Liambaya. 2009

机译：抗原位点突变对抗血凝素抗体与H3N2流感病毒分离株结合特异性的影响。
6. Challenges in Antigenic Characterization of Circulating Influenza A(H3N2) Viruses during the 2011-2012 Influenza Season: an Ongoing Problem? [O] . Athanasios Kossyvakis, Vasiliki Pogka, Aggeliki Melidou, 2015

机译：在2011-2012年流感季节期间循环型A（H3N2）病毒的抗原表征面临的挑战：一个持续存在的问题？
7. Prevalence of antibodies against seasonal influenza A and B viruses during the 2009-2010 and 2010-2011 influenza seasons in residents of Pittsburgh, PA, USA. [O] . Ross, Ted M., Hairong, Lu, Chia, Bing Shao, 2011

机译：在美国宾夕法尼亚州匹兹堡的居民中，针对2009-2010年和2010-2011年流感季节的季节性甲型和乙型流感病毒抗体的流行率。
8. Health Hazard Evaluation Report: HETA-2010-0019 and 2010-0021-3120, January 2011. Environmental Assessment for the Presence of Influenza Viruses (2009 Pandemic Influenza A H1N1 and Seasonal) in Dental Practices - Ohio [R] . Ahrenholz, S. H., Brueck, S. E., de Perio, M. A. 2011

机译：健康危害评估报告：HETa-2010-0019和2010-0021-3120，2011年1月。在牙科诊所中对流感病毒（2009年甲型H1N1流感和季节性流感）的存在进行环境评估 - 俄亥俄州

Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010–2011 influenza season: high prevalence of mutations at antigenic sites

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