Optimization of 11Cmethionine PET study: appropriate scan timing and effect of plasma amino acid concentrations on the SUV

摘要

Background[¹¹C]methionine (MET) has been used to monitor amino acid metabolism in tumors, the pancreas, liver, and myocardium. The aim of the present study was to standardize [¹¹C]MET positron emission tomography (PET) by optimizing the timing of initiation of the scan and applying correction to the plasma concentrations of neutral amino acids (NAAs), where necessary.