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Variation of choroidal thickness and vessel diameter in patients with posterior non-infectious uveitis

机译:后非感染性葡萄膜炎患者脉络膜厚度和血管直径的变化

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摘要

BackgroundChoroidal thickness (CTh) and choroidal vessel diameter (VD) in the Haler’s layer were evaluated as markers of inflammatory insult in non-infectious uveitis (NIU). Spectral-domain optical coherence tomography (Spectralis®, Heidelberg Engineering Inc.) scans were acquired from 23 normal subjects (39 eyes – group 1), 7 subjects with high myopia (14 eyes – group 2), and 19 patients with NIU (23 eyes – group 3). In groups 1 and 2, CTh and VD were measured at 3 different points of the same horizontal OCT scan passing through the fovea and a mean calculated. Mean CTh and VD were calculated in 2 other locations, 2 mm superior and inferior from the chosen foveal horizontal scan. In group 3, three measurements of CTh and VD were obtained within 1 mm of a horizontal scan passing through a retinal lesion; mean CTh and VD were then computed. A ratio (R) between the VD and the corresponding CTh was calculated.
机译:背景技术Haler层中的脉络膜厚度(CTh)和脉络膜血管直径(VD)被评估为非感染性葡萄膜炎(NIU)炎性损伤的标志。光谱域光学相干断层扫描(Spectralis®,海德堡工程公司)扫描来自23名正常受试者(39眼–第1组),7名高度近视受试者(14眼–第2组)和19例NIU患者(23)眼睛-第3组)。在第1组和第2组中,在同一水平OCT扫描穿过中央凹的3个不同点处测量了CTh和VD,并计算了平均值。平均CTh和VD在其他2个位置(从所选的中央凹水平扫描处上下2 mm)计算。在第3组中,在通过视网膜病变的水平扫描的1毫米内获得了三项CTh和VD的测量值。然后计算平均CTh和VD。计算了VD和相应的CTh之间的比率(R)。

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