Simultaneous PET/MRI with 13C magnetic resonance spectroscopic imaging (hyperPET): phantom-based evaluation of PET quantification

摘要

BackgroundIntegrated PET/MRI with hyperpolarized ¹³C magnetic resonance spectroscopic imaging (¹³C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absence of interference between the two modalities. This has been documented for a clinical whole-body system using simultaneous ¹H-MRI and PET but never for ¹³C-MRSI and PET. Here, the feasibility of simultaneous PET and ¹³C-MRSI as well as hyperpolarized ¹³C-MRSI in an integrated whole-body PET/MRI hybrid scanner is evaluated using phantom experiments.