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Measurement of skin surface dose distributions in radiation therapy using poly(vinyl alcohol) cryogel dosimeters

机译:使用聚乙烯醇冷冻凝胶剂量计在放射治疗中测量皮肤表面剂量分布

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摘要

In external beam radiation therapy (EBRT), skin dose measurement is important to evaluate dose coverage of superficial target volumes. Treatment planning systems (TPSs) are often inaccurate in this region of the patient, so in vivo measurements are necessary for skin surface dose estimation. In this work, superficial dose distributions were measured using radiochromic translucent poly(vinyl alcohol) cryogels. The cryogels simultaneously served as bolus material, providing the necessary buildup to achieve the desired superficial dose. The relationship between dose to the skin surface and dose measured with the bolus was established using a series of oblique irradiations with gantry angles ranging from 0° to 90°. EBT‐2 Gafchromic film was placed under the bolus>, and the ratio of bolus‐film dose was determined ranging from 0.749 ± 0.005 to 0.930 ± 0.002 for 0° and 90° gantry angles, respectively. The average ratio over 0–67.5° (0.800 ± 0.064) was used as the single correction factor to convert dose in bolus to dose to the skin surface. The correction factor was applied to bolus measurements of skin dose from head and neck intensity‐modulated radiation therapy (IMRT) treatments delivered to a RANDO phantom. The resulting dose distributions were compared to film measurements using gamma analysis with a 3%/3 mm tolerance and a 10% threshold. The minimum gamma pass rate was 95.2% suggesting that the radiochromic bolus may provide an accurate estimation of skin surface dose using a simple correction factor. This study demonstrates the suitability of radiochromic cryogels for superficial dose measurements in megavoltage photon beams.
机译:在外部束放射疗法(EBRT)中,皮肤剂量测量对于评估浅表目标体积的剂量覆盖范围很重要。在患者的该区域中,治疗计划系统(TPS)通常不准确,因此需要进行体内测量以估算皮肤表面剂量。在这项工作中,使用放射色半透明的聚乙烯醇冷凝胶测量了表面剂量分布。冷冻凝胶同时用作推注材料,提供必要的堆积以达到所需的表面剂量。使用一系列倾斜扫描,在0°至90°范围内的龙门架角度建立皮肤表面剂量与推注剂量之间的关系。将EBT-2 Gafchromic薄膜放置在大剂量下(>),确定0°和90°机架角度的大剂量薄膜剂量比范围为0.749±0.005至0.930±0.002。将0–67.5°(0.800±0.064)上的平均比率用作单一校正因子,以将大剂量的剂量转换为皮肤表面的剂量。校正因子用于推注从RANDO体模上进行的头颈部强度调制放射疗法(IMRT)治疗的皮肤剂量的大剂量测量。将所得的剂量分布与使用伽玛分析(3%/ 3 mm公差和10%阈值)的胶片测量结果进行比较。最低伽玛通过率是95.2%,表明放射致变团可以使用简单的校正因子来准确估计皮肤表面剂量。这项研究证明了放射性变色冰晶凝胶适用于兆伏光子束中的表面剂量测量。

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