Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine

摘要

Background:Faster acting antidepressants and biomarkers that predict treatment response are needed to facilitate the development of more effective treatments for patients with major depressive disorders. Here, we evaluate implicitly and explicitly processed emotional faces using neuroimaging to identify potential biomarkers of treatment response to the antimuscarinic, scopolamine.