Efficacy of Oral Vancomycin Oral Metronidazole or IV Metronidazole Prophylaxis at Reducing the Risk of Clostridium difficile Recurrence

摘要

BackgroundSecondary prophylaxis (SP) for Clostridium difficile infection (CDI) with oral vancomycin or oral/IV metronidazole when initiating antibiotics is common, though few studies are available to support this practice. The purpose of this study was to assess the efficacy of prophylaxis within a year of index CDI.