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Immune Senescence Factors Associated with the Immunogenicity of a Live Attenuated Zoster Vaccine (ZV) in Older Adults

机译：与老年人减毒活的带状疱疹疫苗（ZV）的免疫原性相关的免疫衰老因子。

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BackgroundZV confers protection against herpes zoster by increasing the cell-mediated immunity (CMI) to varicella-zoster virus (VZV). ZV immunogenicity and protection decrease with increasing age. We investigated effects of age and immune senescence on ZV immunogenicity.

机译：BackgroundZV通过增加针对水痘带状疱疹病毒（VZV）的细胞介导的免疫（CMI），赋予针对带状疱疹的保护。 ZV的免疫原性和保护作用随着年龄的增长而降低。我们调查了年龄和免疫衰老对ZV免疫原性的影响。

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期刊名称 Open Forum Infectious Diseases
作者
Adriana Weinberg; Kenneth Schamder; Michael Johnson; Zoran Popmihajlov; Adriana Tovar-Salazar; Yupanqui Caldas; Lei Pang; Alice Cho; Myron Levin;
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作者单位

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年(卷),期 2017(4),Suppl 1
年度 2017
页码 S413–S414
总页数 2
原文格式 PDF
正文语种
中图分类病毒传染病;
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专利

1. Immunogenicity and Safety of the HZ/su Adjuvanted Herpes Zoster Subunit Vaccine in Adults Previously Vaccinated With a Live Attenuated Herpes Zoster Vaccine [J] . Grupping Katrijn, Campora Laura, Douha Martine, The Journal of Infectious Diseases . 2017,第11期

机译：Hz / Su辅助疱疹的免疫原性和安全性在先前用活衰减疱疹疫苗接种的成人接种的成人中的亚氏乳腺疫苗
2. Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults [J] . Weinberg Adriana, Canniff Jennifer, Rouphael Nadine, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2017,第2期

机译：VariCella-Zoster病毒特异性细胞免疫应答对年轻和老年人的活病毒疫苗
3. Varicella-Zoster Virus–Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults [J] . Adriana Weinberg, Jennifer Canniff, Nadine Rouphael, The journal of immunology . 2017,第2期

机译：水痘带状疱疹病毒对活的减毒带状疱疹疫苗的特定细胞免疫反应在年轻人和老年人中。
4. A double-blind, randomized phase II trial of thesafety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adults [C] . Shelly A. McNeil, Scott A. Halperin, Joanne M. Langley, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：一种双盲，随机期II试验，对健康成人的26岁的26岁群体的疫苗疫苗
5. Engineering a live attenuated vaccine: Mutational analysis of varicella-zoster virus (VZV) glycoproteins,gI andgE, in recombinant VZV strains. [D] . Mallory, Suzanne. 1997

机译：设计减毒活疫苗：重组VZV株中水痘带状疱疹病毒（VZV）糖蛋白，gI和gE的突变分析。
6. Immunogenicity and Safety of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults Previously Vaccinated with a Live-Attenuated Herpes Zoster Vaccine: A Phase III Group-Matched Clinical Trial [O] . Katrijn Grupping, Laura Campora, Martine Douha, 2017

机译：以前曾接种过活性带状疱疹带状疱疹疫苗的成年人中佐剂性带状疱疹亚基疫苗的免疫原性和安全性：III期小组配对的临床试验
7. The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity [O] . Adriana Weinberg, Lei Pang, Michael J. Johnson, 2019

机译：通过基线调节性T细胞和种子果蛋杆菌病毒特异性T细胞免疫预测年龄对活病变疫苗的免疫原性的影响

Immune Senescence Factors Associated with the Immunogenicity of a Live Attenuated Zoster Vaccine (ZV) in Older Adults

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