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Edaravone acts as a potential therapeutic drug against pentylenetetrazole‐induced epilepsy in male albino rats by downregulating cyclooxygenase‐II

机译：依达拉奉可通过下调环氧合酶II作为雄性白化病大鼠中戊戊四唑诱发的癫痫的潜在治疗药物

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IntroductionThe effects of edaravone against pentylenetetrazole (PTZ)‐induced epilepsy in male albino rats were investigated. Edaravone is a well‐known commercial drug used in the treatment of strokes and amyotrophic lateral sclerosis (ALS). Antioxidant and free radical scavenging activities of edaravone have been reported in patients with ALS.

机译：简介研究了依达拉奉对戊四氮（PTZ）诱发的雄性白化病大鼠癫痫的影响。依达拉奉是一种著名的商业药物，用于治疗中风和肌萎缩性侧索硬化症（ALS）。依达拉奉具有抗氧化和清除自由基的活性，已报道患有ALS患者。

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期刊名称 Brain and Behavior
作者
Liang‐min Liu; Ning Wang; Yan Lu; Wei‐ping Wang;
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作者单位

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年(卷),期 2019(9),1
年度 2019
页码 e01156
总页数 8
原文格式 PDF
正文语种
中图分类医学行为学;
关键词
antioxidant apoptosis cyclooxygenase edaravone rats;

机译：抗氧化剂;细胞凋亡;环氧合酶;依达拉奉;大鼠;

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专利

1. Edaravone acts as a potential therapeutic drug against pentylenetetrazole‐induced epilepsy in male albino rats by downregulating cyclooxygenase‐II [J] . Liang‐min Liu, Ning Wang, Yan Lu, Brain and Behavior . 2018,第1期

机译：依达拉奉可通过下调环氧合酶II来作为抗戊烯四唑诱发的男性白化病癫痫的潜在治疗药物
2. Potential therapeutic and protective effect of curcumin against stroke in the male albino stroke-induced model rats [J] . Yuanyuan Zhang, Yi Yan, Yi Cao, Life sciences . 2017,第期

机译：姜黄素对患者患者患者在雄性白血病中风诱导的模型大鼠中的潜在治疗和保护作用
3. Valsartan prevents glycerol-induced acute kidney injury in male albino rats by downregulating TLR4 and NF-kappa B expression [J] . Sun Xiuju, Luan Qingxia, Qiu Shujuan International Journal of Biological Macromolecules: Structure, Function and Interactions . 2018,第期

机译：缬沙坦通过下调TLR4和NF-Kappa B表达，通过下调甘油诱导甘油诱导的雄性肾脏损伤
4. Evaluation of anti-hepatotoxic potential of Cassia javanica (L.) methanol extract against paracetamol-induced liver damage in Wistar albino rats [C] . Esther Lalhmingliani, Zodinpuii, R.K. Lalremtluangi, Mizoram Science Congress . 2019

机译：Cassia Javanica（L.）甲醇提取抗丙基莫醇诱导肝癌肝损伤的抗肝毒性潜力评价Wistar Albino大鼠
5. DURATION OF ACUTE AND SUBACUTE CENTRAL SAR(1)-ILE(8)-ANGIOTENSIN II ANTAGONISM OF THE CENTRAL ANGIOTENSIN II AND III - INDUCED PRESSOR RESPONSE IN NORMOTENSIVE MALE RATS. [D] . MORSETH, SANDRA LYNN. 1985

机译：急性和急性中枢SAR（1）-ILE（8）-血管紧张素II的持续时间中央血管紧张素II和III的拮抗作用-诱导了非致敏性雄性大鼠的压力反应。
6. Cyclooxygenase-1 as a Potential Therapeutic Target for Seizure Suppression: Evidences from Zebrafish Pentylenetetrazole-Seizure Model [O] . Patrícia Gonçalves Barbalho, Benilton de Sá Carvalho, Iscia Lopes-Cendes, 2016

机译：环氧合酶-1作为癫痫发作抑制的潜在治疗靶标：来自斑马鱼戊四烯-癫痫发作模型的证据
7. Edaravone acts as a potential therapeutic drug against pentylenetetrazole-induced epilepsy in male albino rats by downregulating cyclooxygenase-II [O] . Liang-min Liu, Ning Wang, Yan Lu, 2018

机译：埃及龙酮作为潜在的治疗药物，通过下调环氧基酶-II，作为雄性白化大鼠癫痫患者的潜在治疗药物。

Edaravone acts as a potential therapeutic drug against pentylenetetrazole‐induced epilepsy in male albino rats by downregulating cyclooxygenase‐II

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