首页> 美国卫生研究院文献>Schizophrenia Bulletin >F27. LATENT PROFILES OF DEVELOPMENTAL SCHIZOTYPY IN THE GENERAL POPULATION: ASSOCIATIONS WITH CHILDHOOD TRAUMA AND FAMILIAL MENTAL ILLNESS
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F27. LATENT PROFILES OF DEVELOPMENTAL SCHIZOTYPY IN THE GENERAL POPULATION: ASSOCIATIONS WITH CHILDHOOD TRAUMA AND FAMILIAL MENTAL ILLNESS

机译:F27。普通人群发育型精神分裂症的潜伏特征:与儿童创伤和家族性精神疾病的关系

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摘要

BackgroundLatent liability for schizophrenia (schizotypy) is expressed in various combinations of cognitive, psychological, and behavioural characteristics evident in the general population. Historical models propose that distinct classes of individuals expressing different forms of schizotypy may represent manifestations of differential levels of genetic and environmental risk for schizophrenia (or related illness). However, there has been little investigation of developmental models of schizotypy in childhood. Here, we sought to delineate latent profiles of schizotypy among children aged 11–12 years, and to examine associations between emerging schizotypal profiles and parental history of mental illness (as a proxy for genetic risk), early life trauma, and childhood contact with health services for mental illness up to age 13 years.
机译:背景精神分裂症(精神分裂症)的潜在责任以普通人群中明显的认知,心理和行为特征的各种组合表达。历史模型表明,表达不同形式的精神分裂症的不同类别的个体可能代表精神分裂症(或相关疾病)的遗传和环境风险水平的差异。但是,关于儿童精神分裂症发展模型的研究很少。在这里,我们试图描绘11-12岁儿童的精神分裂症的潜在特征,并研究新兴的精神分裂症特征与父母的精神病史(作为遗传风险的代表),生命早期创伤以及儿童期接触健康之间的关联。 13岁以下精神疾病服务。

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