Evaluation of 3-(45-dimethylthiazol-2-yl)-25-diphenyl tetrazolium bromide method for assessing biofilm formation in vitro by Trichosporon spp.

摘要

BACKGROUND:Invasive infections due to Trichosporon spp. have increased recently and are frequently associated with indwelling medical devices. Such infections which are associated with biofilm formation do not respond to the routinely used antifungal agents and are often persistent, associated with high mortality rate. Various methods have been described by researchers to evaluate and quantify the biofilm formation.