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The Impact of Hepatitis C Virus Direct-Acting Antivirals on Patient-Reported Outcomes: A Dutch Prospective Cohort Study

机译：丙型肝炎病毒直接作用抗病毒药对患者报告结果的影响：一项荷兰前瞻性队列研究

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IntroductionPegylated interferon-based therapy for hepatitis C virus (HCV) negatively impacts nutritional state and patient-reported outcomes (PROs) such as health-related quality of life (HRQL). Clinical trials with direct-acting antivirals (DAAs) report significant PRO improvement but real-world data are still scarce.

机译：简介基于聚乙二醇干扰素的丙型肝炎病毒（HCV）治疗会对营养状况和患者报告的结局（PRO）（例如与健康相关的生活质量（HRQL））产生负面影响。使用直接作用抗病毒药（DAA）的临床试验报告PRO有了显着改善，但实际数据仍然很少。

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期刊名称 Infectious Diseases and Therapy
作者
Patricia A. M. Kracht; Faydra I. Lieveld; Linde M. Amelung; Carina J. R. Verstraete; Eveline P. Mauser-Bunschoten; Joep de Bruijne; Peter D. Siersema; Andy I. M. Hoepelman; Joop E. Arends; Karel J. van Erpecum;
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年(卷),期 2018(7),3
年度 2018
页码 373–385
总页数 13
原文格式 PDF
正文语种
中图分类病毒传染病;
关键词
Adherence Beliefs about Medicines Direct-acting antivirals Health-related quality of life Hepatitis C virus Karnofsky performance status;

机译：坚持;关于药物的信念;直接作用的抗病毒药;与健康有关的生活质量;丙型肝炎病毒;卡诺夫斯基机能状态;

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1. The Impact of Hepatitis C Virus Direct-Acting Antivirals on Patient-Reported Outcomes: A Dutch Prospective Cohort Study [J] . Patricia A. M. Kracht, Faydra I. Lieveld, Linde M. Amelung, Infectious Diseases and Therapy . 2018,第3期

机译：丙型肝炎病毒直接作用抗病毒药对患者报告结果的影响：荷兰前瞻性队列研究
2. Clinical and Patient-Reported Outcomes of Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C Among Patients on Opioid Agonist Treatment: A Real-world Prospective Cohort Study [J] . Bernd Schulte, Christiane S Schmidt, Jakob Manthey, Open Forum Infectious Diseases . 2020,第8期

机译：临床和患者报告用于治疗阿片类激动剂治疗患者慢性丙型肝炎的直接作用抗病毒的结果：一个现实世界预期队列研究
3. Preliminary clinical outcome data among patients with hepatitis C virus infection receiving direct-acting antiviral therapy in the Chronic Hepatitis Cohort Study, 2014-2015 [J] . Spradling Philip R., Xing Jian, Rupp Loralee B., Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2016,第S1期

机译：丙型肝炎病毒感染患者初步临床结果数据，慢性肝炎群体研究中接受直效抗病毒治疗，2014-2015
4. Herbal Medicine Containing Aristolochic Acid and the Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection: A Nationwide Population-Based Cohort Study in Taiwan [C] . Wen-Chao Ho, Chi-Jen Chen, Yao-Hsu Yang, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：含有马兜铃酸的草药和丙型肝炎病毒感染患者肝细胞癌的风险：台湾全国性人群研究
5. Analyzing the Impact of the CMS Guidance on Assuring Access to Hepatitis C Virus (HCV) Drugs on Utilization of Direct-Acting Antiviral (DAA) Agents [D] . Ferrell, Kelli Walker. 2017

机译：分析CMS指南对确保获得丙型肝炎病毒（HCV）药物对直接作用抗病毒（DAA）药物利用的影响
6. Clinical and Patient-Reported Outcomes of Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C Among Patients on Opioid Agonist Treatment: A Real-world Prospective Cohort Study [O] . Bernd Schulte, Christiane S Schmidt, Jakob Manthey, 2020

机译：临床和患者报告用于治疗阿片类激动剂治疗患者慢性丙型肝炎的直接作用抗病毒的结果：一个现实世界预期队列研究
7. Clinical and Patient-Reported Outcomes of Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C Among Patients on Opioid Agonist Treatment: A Real-world Prospective Cohort Study [O] . Bernd Schulte, Christiane S Schmidt, Jakob Manthey, 2020

机译：临床和患者报告用于治疗阿片类激动剂治疗患者慢性丙型肝炎的直接作用抗病毒的结果：一个现实世界预期队列研究

The Impact of Hepatitis C Virus Direct-Acting Antivirals on Patient-Reported Outcomes: A Dutch Prospective Cohort Study

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