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A clash at the petri dish: transferring embryos with known genetic anomalies

机译:培养皿上的冲突:转移具有已知遗传异常的胚胎

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摘要

Advancing technologies in genetic testing of preimplantation embryos enable IVF patients to access detailed information about their future child's health status, facilitating and complicating their reproductive decision-making. Testing for embryonic genetic anomalies linked to future health has grown increasingly sophisticated. A patient's decision to seek transfer of a health-affected embryo may or may not be compatible with her physician's professional conscience, potentially resulting in a clash at the petri dish. This article sets out arguments in support of physician decisions to assist or decline to assist in the transfer of anomalous embryos upon patient request. Arguments in support of transfer include the preeminence of a patient's reproductive liberty, the value of equal protection as applied to pre- and post-implantation embryos, the allocation of dispositional authority over embryos, and the frailties of predicting a child's future health experience. Arguments that bolster a provider's decision to decline requests for transfer include the role of physician autonomy in the doctor-patient relationship, the theories of reproductive non-maleficence and procreative beneficence, and legitimate concerns over future legal liability. Regardless of a clinic's ultimate position, this article advocates that providers create or adopt detailed policies setting forth their preferences and practices regarding anomalous embryo transfer.
机译:植入前胚胎的基因测试中的先进技术使IVF患者能够获得有关其未来孩子健康状况的详细信息,从而使他们的生殖决策更加复杂化。与未来健康相关的胚胎遗传异常的测试变得越来越复杂。患者寻求转移受健康影响的胚胎的决定可能与她的医师的专业良心不相容,可能导致培养皿发生冲突。本文提出了支持医师决定协助或拒绝协助根据患者要求转移异常胚胎的论点。支持移植的论点包括患者生殖自由的优越性,植入前和植入后胚胎受到同等保护的价值,对胚胎的处置权的分配以及预测儿童未来健康经验的脆弱性。支持提供者拒绝转移请求的决定的论点包括医师自主权在医患关系中的作用,生殖非恶意和生殖性受益的理论以及对未来法律责任的合理关注。无论诊所的最终地位如何,本文都建议提供者制定或采用详细的政策,阐明他们对异常胚胎移植的偏好和做法。

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