Optimized dual-time-window protocols for quantitative 18Fflutemetamol and 18Fflorbetaben PET studies

摘要

BackgroundA long dynamic scanning protocol may be required to accurately measure longitudinal changes in amyloid load. However, such a protocol results in a lower patient comfort and scanning efficiency compared to static scans. A compromise can be achieved by implementing dual-time-window protocols. This study aimed to optimize these protocols for quantitative [¹⁸F]flutemetamol and [¹⁸F]florbetaben studies.