Association between clinicopathologic characteristics and BRAFV600E expression in Chinese patients with Langerhans cell histiocytosis

摘要

BackgroundThe identification of V‐raf murine sarcoma viral oncogene homolog B1 (BRAF)^V600E mutations has been recommended in patients with Langerhans cell histiocytosis (LCH) with difficult diagnosis and failure of first‐line treatment. The reported frequencies of BRAF^V600E mutations vary in Chinese patients with LCH.