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Patient-level clinically meaningful improvements in activities of daily living and pain after total hip arthroplasty: data from a large US institutional registry

机译:全髋关节置换术后患者活动方面的临床意义上有意义的改善包括日常生活和疼痛活动:来自大型美国机构注册机构的数据

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摘要

>Objective. To characterize patient-level clinically meaningful improvements in pain and limitation of key activities of daily living (ADLs) after primary or revision total hip arthroplasty (THA).>Methods. We analysed prospectively collected data from the Mayo Clinic Total Joint Registry to study clinically meaningful improvements in index hip pain severity and limitation in seven key ADLs (walking, climbing stairs, putting on shoes/socks, picking up objects, getting in/out of car, rising from a chair and sitting), from preoperative to 2- and 5-year post-THA.>Results. The primary THA cohort consisted of 6168 responders preoperatively, 5707 at 2 years and 3289 at 5 years postoperatively. The revision THA cohort consisted of 2063 responders preoperatively, 2682 at 2 years and 1627 at 5 years postoperatively. In the primary THA cohort, clinically meaningful pain reduction to mild or no hip pain at 2 years was reported by 94% with moderate and 91% with severe preoperative pain; respective proportions were 91% and 89% at 5-year follow-up. For revision THA, respective proportions were 84% and 77% at 2 years and 80% and 78% at 5 years. In the primary THA cohort, up to 4% with moderate and 17% with severe preoperative ADL limitation reported severe limitation in the respective activity 2 years post-primary THA; at 5 years, the respective proportions were up to 7% and 20%. Respective proportions for revision THA were up to 10% and 26% at 2 years and 13% and 30% at 5 years.>Conclusions. These comprehensive data for patient-level clinically meaningful improvements in pain and seven key ADLs can help patients set realistic goals for improvement after THA.
机译:>目的。在初诊或翻修全髋关节置换术(THA)后,表征患者水平的临床意义上的疼痛改善和日常生活关键活动限制(ADL)。>方法。我们分析了从Mayo诊所总关节登记处收集的前瞻性数据,以研究在七个关键ADL(步行,爬楼梯,穿鞋/袜子,捡起物体,上车/下车)对指数髋痛严重程度和限制的临床意义上的改善(从椅子和坐位开始),从术前到术后2年和5年。>结果。 THA的主要队列包括术前6168例反应者,2年时5707例和5年时3289例。术后。修订后的THA队列由术前2063人,术后2年2682人,术后5年1627人组成。在原发性THA队列中,据报道2年时有94%的中度患者减轻疼痛至轻度或无髋部疼痛的临床意义,而术前严重疼痛则为91%。五年随访时分别为91%和89%。对于THA修订版,在2年时分别占84%和77%,在5年时分别占80%和78%。据报道,在原发性THA人群中,术前ADL限制为中度的有4%,严重的术前ADL限制为17%,据报道在原发性THA后2年的活动受到严重限制。在5年时,各自的比例分别达到7%和20%。修订THA的比例分别在2年时分别达到10%和26%,在5年时分别达到13%和30%。>结论。这些综合数据可为患者提供临床上有意义的疼痛改善和七个关键指标ADL可帮助患者设定THA后改善的现实目标。

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