Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats

机译：海马5-HT1A受体介导的cAMP / PKA信号通路在七氟醚引起的老年大鼠认知功能障碍中的作用

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摘要

ObjectiveThis study aimed to evaluate the role of the hippocampal 5-hydroxytryptamine-1A (5-HT1A)-mediated cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) signalling pathway in sevoflurane-induced cognitive dysfunction in aged rats.

机译：目的本研究旨在评估海马5-羟色胺1A（5-HT1A）介导的环磷酸单腺苷/蛋白激酶A（cAMP / PKA）信号通路在七氟醚引起的老年大鼠认知功能障碍中的作用。

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期刊名称 The Journal of International Medical Research
作者
Yi Qiu; Ying Wang; Xiaodong Wang; Caixia Wang; Zhong-yuan Xia;
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作者单位

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年(卷),期 2018(46),3
年度 2018
页码 1073–1085
总页数 13
原文格式 PDF
正文语种
中图分类药学;医学史;
关键词
Cyclic adenosine monophosphate 5-hydroxytryptamine-1A receptor protein kinase A sevoflurane cognitive dysfunction cerebral hippocampus;

机译：环状磷酸腺苷;5-羟色胺-1A受体;蛋白激酶A;七氟醚;认知功能障碍;脑海马;

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专利

1. Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats [J] . Yi Qiu, Ying Wang, Xiaodong Wang, Journal of International Medical Research . 2018,第3期

机译：海马5-HT1A受体介导的cAMP / PKA信号通路在七氟醚引起的老年大鼠认知功能障碍中的作用
2. Electroacupuncture ameliorates learning and memory deficits via hippocampal 5-HT1A receptors and the PKA signaling pathway in rats with ischemic stroke [J] . Wang Zhifu, Lin Bingbing, Liu Weilin, Metabolic brain disease . 2020,第3期

机译：通过海马5-HT1A受体和缺血性卒中大鼠的PKA信号通路改善了学习和记忆缺陷
3. Enhancement of hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by repeated lithium treatment in rats. [J] . Fujii T, Nakai K, Nakajima Y, Canadian Journal of Physiology and Pharmacology . 2000,第5期

机译：通过反复的锂治疗，通过5-HT1A受体介导的途径增强海马胆碱能神经传递。
4. PingYu Capsule Activates cAMP/PKA/CREB Signaling Pathway in Rat Hippocampus: A Possible Mechanism for Antidepressant-Like Effect [C] . Jun-Sheng Tian, Yuan-Lu Cui, Zuo-Guang Zhang Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009 . 2009

机译：平鱼胶囊激活大鼠海马中的cAMP / PKA / CREB信号通路：一种抗抑郁样作用的可能机制
5. The role of two novel kelch proteins Krh1 and Krh2 in the Gpa2p-cAMP/PKA signaling pathway in Saccharomyces cerevisiae. [D] . Lu, Ailan. 2004

机译：两种新的海藻蛋白Krh1和Krh2在酿酒酵母中Gpa2p-cAMP / PKA信号通路中的作用。
6. Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol-induced neurotoxicity in the hippocampus of neonatal rats [O] . Ruicong Guan, Jing Lv, Fei Xiao, -1

机译：cAMP / PKA / CREB信号通路在缺氧预处理中的潜在作用以及对异丙酚诱导的新生大鼠海马神经毒性的影响
7. Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway [O] . Tie-Jun Liu, Jin-Cun Zhang, Xiao-Zeng Gao, 2018

机译：七氟醚对camp-pKa信号通路大鼠脑缺血再灌注损伤后海马神经元aTp酶活性的影响

Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats

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