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Constructal law analysis of Cl− transport in eyes aqueous humor

机译:眼房水Cl-转运的构造规律分析

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摘要

Progressive loss-of-vision related to any intraocular disorder is known as glaucoma. Secretion of aqueous humor is physiologically important to provide nutrients and oxygen to the avascular anterior segment and ensuring normal visual function, even if, nowadays reducing the secretory rate to lower intraocular pressure is a major strategy in treating glaucomatous patients. Understanding the mechanisms and regulation of aqueous humor formation is very important to develop possible new approaches to lower intraocular pressure,but today there isn’t any comprehensive model of the regulation of these component in forming aqueous humor. In this paper Construcal law is used to suggest how the Cl fluxes can determine the water inflow and outflow, and, consequently, how the intraocular pressure is controlled by these fluxes.
机译:与任何眼内疾病有关的进行性视力减退被称为青光眼。房水的分泌对于向血管前段提供营养和氧气并确保正常的视觉功能在生理上是重要的,即使如今降低分泌率以降低眼内压是治疗青光眼患者的主要策略。了解房水形成的机制和调控对于开发降低眼内压的新方法非常重要,但是今天,尚无关于这些成分在房水形成中调控的全面模型。在本文中,构造定律被用来建议Cl -通量如何确定水的流入和流出,以及因此如何通过这些通量控制眼压。

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