A Petal-type Chiral NADH Model: Design Synthesis and its Asymmetric Reduction

摘要

A new type of NADH model compound has been synthesized by an efficient and convenient method. This model compound exhibits high reactivity and enantioselectivity in asymmetric reduction reactions. The results show that chiral NADH model >S could be effectively combined with Mg²⁺ to form ternary complexes. This novel C3 symmetrical NADH model is capable of fluorescence emission at 460 nm when excited at 377 nm.