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Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis

机译:射频消融联合TACE治疗乳腺癌肝转移的临床研究

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摘要

We studied the clinical effects of percutaneous radiofrequency ablation (RFCA) combined with trans-catheter arterial chemoembolization (TACE) in the treatment of breast cancer with liver metastasis. Eighty-eight patients with a diagnosis of breast cancer with liver metastasis for the first time and patients with liver metastasis after radical mastectomy were consecutively selected. The subjects were divided according to the different treatment methods. They were divided either into the control group of 50 cases or the observation group of 38 cases. Breast cancer patients underwent radical mastectomy with conventional systemic venous chemotherapy. The liver metastasis control group used TACE, while the observation group combined RFCA with TACE. The two groups were followed up for a median time of 20 months, and the clinical effects were compared. The effective rate of the observation group was higher than that of the control group; differences were statistically significant (P<0.05). There was no differences in the incidence of complications between the two groups (P>0.05). The progression free survival, median survival time and survival rate of the observation group were increased; differences were statistically significant (P<0.05). Therefore, RFCA combined with TACE in the treatment of breast cancer with liver metastasis is safe and effective.
机译:我们研究了经皮射频消融(RFCA)结合经导管动脉化疗栓塞(TACE)在治疗具有肝转移的乳腺癌中的临床效果。连续选择了88例首次诊断为具有肝转移的乳腺癌患者和根治性乳房切除术后的肝转移患者。根据不同的治疗方法对受试者进行划分。他们分为对照组50例或观察组38例。乳腺癌患者采用常规全身静脉化疗进行了根治性乳房切除术。肝转移对照组采用TACE,观察组采用RFCA和TACE。两组均接受随访,平均时间为20个月,并比较了临床效果。观察组有效率高于对照组。差异具有统计学意义(P <0.05)。两组并发症发生率无差异(P> 0.05)。观察组无进展生存期,中位生存时间和生存率增加;差异具有统计学意义(P <0.05)。因此,RFCA联合TACE治疗乳腺癌并发肝转移是安全有效的。

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