Early Morning Executive Functioning During Sleep Deprivation Is Compromised by a PERIOD3 Polymorphism

摘要

Study Objectives:To contrast the effects of total sleep deprivation (TSD) on executive and non-executive function in volunteers homozygous for either the short or long variant of a variable number tandem repeat polymorphism in PERIOD3, which is a genetic marker for susceptibility to the negative effect of sleep loss on waking performance.