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Invariance properties of bacterial random walks in complex structures

机译:复杂结构中细菌随机游动的不变性

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摘要

Motile cells often explore natural environments characterized by a high degree of structural complexity. Moreover cell motility is also intrinsically noisy due to spontaneous random reorientations and speed fluctuations. This interplay of internal and external noise sources gives rise to a complex dynamical behavior that can be strongly sensitive to details and hard to model quantitatively. In striking contrast to this general picture we show that the mean residence time of swimming bacteria inside artificial complex microstructures is quantitatively predicted by a generic invariance property of random walks. We find that while external shape and internal disorder have dramatic effects on the distributions of path lengths and residence times, the corresponding mean values are constrained by the sole free surface to perimeter ratio. As a counterintuitive consequence, bacteria escape faster from structures with higher density of obstacles due to the lower accessible surface.
机译:运动细胞经常探索以高度结构复杂为特征的自然环境。此外,由于自发的随机重新定向和速度波动,细胞运动本身也具有噪声。内部和外部噪声源之间的这种相互作用导致了复杂的动力学行为,该行为可能对细节非常敏感,并且难以进行定量建模。与这一总体情况形成鲜明对比的是,我们表明,游泳细菌在人工复杂微结构内的平均停留时间是由随机游走的一般不变性定量预测的。我们发现,虽然外部形状和内部无序性对路径长度和停留时间的分布有显着影响,但相应的平均值受唯一的自由表面与周长之比的约束。与直觉相反的结果是,由于较低的可及表面,细菌会从具有较高障碍物密度的结构中更快地逸出。

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