Fully automated targeting using non-rigid image registration matches accuracy and exceeds precision of best manual approaches to Subthalamic Deep Brain Stimulation targeting in Parkinsons disease

摘要

BackgroundFinding the optimal location for the implantation of the electrode in Deep Brain Stimulation (DBS) surgery is crucial for maximizing therapeutic benefit to the patient. Such targeting is challenging for several reasons including anatomical variability between patients as well as lack of consensus about the location of the optimal target.