首页> 美国卫生研究院文献>The Journals of Gerontology Series A: Biological Sciences and Medical Sciences >White Blood Cell Counts Insulinlike Growth Factor-1 Levels and Frailty in Community-Dwelling Older Women
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White Blood Cell Counts Insulinlike Growth Factor-1 Levels and Frailty in Community-Dwelling Older Women

机译:在社区居住的老年妇女中白细胞计数胰岛素样生长因子-1水平和虚弱

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摘要

BackgroundElevated white blood cell (WBC) counts and decreased insulin-like growth factor-1 (IGF-1) levels are individually associated with frailty in older adults. WBC subpopulations are known to produce IGF-1 and express IGF-1 receptors in vitro. However, in vivo relationships between WBC and IGF-1 and their joint contribution to frailty have not been investigated.
机译:背景白细胞(WBC)计数升高和胰岛素样生长因子-1(IGF-1)水平降低与老年人的体弱相关。已知WBC亚群可在体外产生IGF-1并表达IGF-1受体。但是,尚未研究WBC和IGF-1之间的体内关系及其对衰弱的共同贡献。

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