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Development of an Automated Steering Mechanism for Bladder Urothelium Surveillance

机译:膀胱尿素监测自动转向机构的研制。

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摘要

Given the advantages of cystoscopic exams compared with other procedures available for bladder surveillance, it would be beneficial to develop an improved automated cystoscope. We develop and propose an active programmable remote steering mechanism and an efficient motion sequence for bladder cancer detection and postoperative surveillance. The continuous and optimal path of the imaging probe can enable a medical practitioner to readily ensure that images are produced for the entire surface of the bladder in a controlled and uniform manner. Shape memory alloy (SMA) based segmented actuators disposed adjacent to the distal end of the imaging probe are selectively activated to bend the shaft to assist in positioning and orienting the imaging probe at a plurality of points selected to image all the interior of the distended bladder volume. The bending arc, insertion depth, and rotational position of the imaging probe are automatically controlled based on patient-specific data. The initial prototype is tested on a 3D plastic phantom bladder, which is used as a proof-of-concept in vitro model and an electromagnetic motion tracker. The 3D tracked tip trajectory results ensure that the motion sequencing program and the steering mechanism efficiently move the image probe to scan the entire inner tissue layer of the bladder. The compared experimental results shows 5.1% tip positioning error to the designed trajectory given by the simulation tool. The authors believe that further development of this concept will help guarantee that a tumor or other characteristic of the bladder surface is not overlooked during the automated cystoscopic procedure due to a failure to image it.
机译:鉴于与其他可用于膀胱监视的程序相比,膀胱镜检查的优势,开发一种改进的自动膀胱镜将是有益的。我们开发并提出了一种主动的可编程远程转向机制以及用于膀胱癌检测和术后监测的有效运动序列。成像探针的连续且最佳的路径可使医学从业者容易地确保以受控且均匀的方式为膀胱的整个表面产生图像。邻近成像探针的远端设置的基于形状记忆合金(SMA)的分段致动器被有选择地激活以弯曲轴,以帮助在选定的多个位置定位和定向成像探针,以选择对膨胀的膀胱内部进行成像的多个点体积。根据患者特定数据自动控制成像探针的弯曲弧度,插入深度和旋转位置。初始原型在3D塑料幻像膀胱上进行了测试,该膀胱用作概念验证的体外模型和电磁运动跟踪器。 3D跟踪的尖端轨迹结果可确保运动排序程序和操纵机构有效地移动图像探针以扫描膀胱的整个内部组织层。比较的实验结果表明,相对于仿真工具给出的设计轨迹,尖端定位误差为5.1%。作者认为,这一概念的进一步发展将有助于确保在自动膀胱镜检查过程中,由于无法成像,因此不会忽略膀胱表面的肿瘤或其他特征。

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