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Accelerated Telomere Shortening Precedes Development of Therapy-Related Myelodysplasia or Acute Myelogenous Leukemia After Autologous Transplantation for Lymphoma

机译：自体移植淋巴瘤后加速端粒缩短成为治疗相关的骨髓增生异常或急性骨髓性白血病的发展。

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PurposeTherapy-related myelodysplasia or acute myelogenous leukemia (t-MDS/AML) is a lethal complication of autologous hematopoietic stem-cell transplantation (aHCT) for Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL). Here, we investigated the hypothesis that accelerated telomere shortening after aHCT could contribute to the development of t-MDS/AML.

机译：目的与治疗有关的骨髓增生异常或急性骨髓性白血病（t-MDS / AML）是自体造血干细胞移植（aHCT）对于霍奇金淋巴瘤（HL）和非霍奇金淋巴瘤（NHL）的致命并发症。在这里，我们调查的假说，aHCT后加速端粒缩短可能有助于t-MDS / AML的发展。

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期刊名称 Journal of Clinical Oncology
作者
Sujata Chakraborty; Can-Lan Sun; Liton Francisco; Melanie Sabado; Liang Li; Karen L. Chang; Stephen Forman; Smita Bhatia; Ravi Bhatia;
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作者单位

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年(卷),期 -1(27),5
年度 -1
页码 791–798
总页数 8
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma. [J] . Chakraborty S, Sun CL, Francisco L, Journal of Clinical Oncology . 2009,第5期

机译：自体移植淋巴瘤后，加速端粒缩短会导致与治疗相关的骨髓增生异常或急性骨髓性白血病。
2. Risk factors before autologous stem-cell transplantation for lymphoma predict for secondary myelodysplasia and acute myelogenous leukemia. [J] . Kalaycio M, Rybicki L, Pohlman B, Journal of Clinical Oncology . 2006,第22期

机译：自体干细胞移植治疗淋巴瘤之前的危险因素可预测继发性骨髓增生异常和急性骨髓性白血病。
3. Therapy-related myelodysplasia and secondary acute myelogenous leukemia after high-dose therapy with autologous hematopoietic progenitor-cell support for lymphoid malignancies. [J] . Micallef IN, Lillington DM, Apostolidis J, Journal of Clinical Oncology . 2000,第5期

机译：自体造血祖细胞支持大剂量治疗淋巴恶性肿瘤后，治疗相关的骨髓增生异常和继发性急性骨髓性白血病。
4. Model (with One Delay) Of Acute Myelogenous Leukemia With Transplantation [C] . Farooqi Z.H. Engineering in Medicine and Biology Society, 1991. Vol.13: 1991., Proceedings of the Annual International Conference of the IEEE . 1991

机译：急性骨髓性白血病移植模型（一延迟）
5. Loss of Egr1 plays a role in murine leukemogenesis and may play a role in the development of acute myeloid leukemia and therapy-related acute myeloid leukemia. [D] . Joslin, John M. 2006

机译：Egr1的丢失在小鼠白血病的发生中起作用，并且可能在急性髓细胞性白血病和与治疗有关的急性髓细胞性白血病的发展中起作用。
6. Altered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia/Acute Myeloid Leukemia and Identifies Patients at Risk [O] . Liang Li, Min Li, Canlan Sun, -1

机译：治疗相关的脊髓发育不良/急性髓系白血病并确定患者的造血改变细胞基因表达先于发展的风险
7. Accelerated Telomere Shortening Precedes Development of Therapy-Related Myelodysplasia or Acute Myelogenous Leukemia After Autologous Transplantation for Lymphoma [O] . Chakraborty, Sujata, Sun, Can-Lan, Francisco, Liton, 2009

机译：自体移植淋巴瘤后，加速端粒缩短成为治疗相关的骨髓增生异常或急性骨髓性白血病的发展。
8. Quantitative Risk Assessment of Exposures to Butadiene in European Union Occupational Settings Based on the University of Alabama at Birmingham Epidemiology Study: Acute Myelogenous Leukemia, Chronic Lymphocytic Leukemia, and Chronic Myelogenous Leukemia [R] . Silken, R. L., Valdez-Flores, C. 2007

机译：基于阿拉巴马大学伯明翰分校的流行病学研究：急性髓性白血病，慢性淋巴细胞白血病和慢性粒细胞白血病，欧盟职业环境中丁二烯暴露的定量风险评估

Accelerated Telomere Shortening Precedes Development of Therapy-Related Myelodysplasia or Acute Myelogenous Leukemia After Autologous Transplantation for Lymphoma

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