Elevated fasting plasma cortisol is associated with ischaemic heart disease and its risk factors in people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study

摘要

ContextIncreased activity of the hypothalamic-pituitary-adrenal (HPA) axis may underlie the metabolic syndrome but whether circulating cortisol levels predict cardiovascular end points is less clear. People with type 2 diabetes are at increased cardiovascular disease risk and thus are suitable to study associations of plasma cortisol with cardiovascular risk.