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CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death Breast Cancer–Specific Death and Increased Risk of a Second Breast Cancer

机译：CHEK2 * 1100delC与早期死亡乳腺癌特定死亡和罹患第二次乳腺癌风险增加相关的乳腺癌女性的杂合性

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摘要

PurposeWe tested the hypotheses that CHEK2*1100delC heterozygosity is associated with increased risk of early death, breast cancer–specific death, and risk of a second breast cancer in women with a first breast cancer.

机译：目的我们检验了以下假设：CHEK2 * 1100delC杂合性与罹患第一例乳腺癌的女性的早期死亡，特定于乳腺癌的死亡以及第二例乳腺癌的风险增加相关。

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期刊名称 Journal of Clinical Oncology
作者
Maren Weischer; Børge G. Nordestgaard; Paul Pharoah; Manjeet K. Bolla; Heli Nevanlinna; Laura J. vant Veer; Montserrat Garcia-Closas; John L. Hopper; Per Hall; Irene L. Andrulis; Peter Devilee; Peter A. Fasching; Hoda Anton-Culver; Diether Lambrechts; Maartje Hooning; Angela Cox; Graham G. Giles; Barbara Burwinkel; Annika Lindblom; Fergus J. Couch; Arto Mannermaa; Grethe Grenaker Alnæs; Esther M. John; Thilo Dörk; Henrik Flyger; Alison M. Dunning; Qin Wang; Taru A. Muranen; Richard van Hien; Jonine Figueroa; Melissa C. Southey; Kamila Czene; Julia A. Knight; Rob A.E.M. Tollenaar; Matthias W. Beckmann; Argyrios Ziogas; Marie-Rose Christiaens; Johanna Margriet Collée; Malcolm W.R. Reed; Gianluca Severi; Frederik Marme; Sara Margolin; Janet E. Olson; Veli-Matti Kosma; Vessela N. Kristensen; Alexander Miron; Natalia Bogdanova; Mitul Shah; Carl Blomqvist; Annegien Broeks; Mark Sherman; Kelly-Anne Phillips; Jingmei Li; Jianjun Liu; Gord Glendon; Caroline Seynaeve; Arif B. Ekici; Karin Leunen; Mieke Kriege; Simon S. Cross; Laura Baglietto; Christof Sohn; Xianshu Wang; Vesa Kataja; Anne-Lise Børresen-Dale; Andreas Meyer; Douglas F. Easton; Marjanka K. Schmidt; Stig E. Bojesen;
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年(卷),期 -1(30),35
年度 -1
页码 4308–4316
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death, Breast Cancer-Specific Death, and Increased Risk of a Second Breast Cancer [J] . Weischer Maren, Nordestgaard Borge G., Pharoah Paul, Journal of Clinical Oncology . 2012,第35期

机译：与早期死亡，特定于乳腺癌的死亡和罹患第二种乳腺癌的风险增加相关的乳腺癌女性患者的CHEK2 * 1100delC杂合性
2. Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2(star)1100delC Heterozygotes Estimated From the Copenhagen General Population Study [J] . Naslund-Koch Charlotte, Nordestgaard Borge G., Bojesen Stig E. Journal of Clinical Oncology . 2016,第11期

机译：根据哥本哈根总人口研究估计，CHEK2（star）1100delC杂合子与乳腺癌相比会增加其他癌症的风险。
3. Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2(star)1100delC Heterozygotes Estimated From the Copenhagen General Population Study [J] . Naslund-Koch Charlotte, Nordestgaard Borge G., Bojesen Stig E. Journal of Clinical Oncology . 2016,第11期

机译：除了Chek2（星）1100delc杂合子的乳腺癌外，其他癌症的风险增加了来自哥本哈根一般人群研究的乳腺癌
4. Automated Breast Tissue Measurement of Women at Increased Risk of Breast Cancer [C] . Patel H. G., Astley S. M., Hufton A. P., International Workshop on Digital Mammography(IWDM 2006) . 2006

机译：乳腺癌风险增加的妇女自动乳腺组织测量
5. Characterization of germline CHEK2 mutations in African-American women at high risk for hereditary breast cancer. [D] . Hill, Janell Glennette. 2009

机译：遗传性乳腺癌高风险的非裔美国女性生殖系CHEK2突变的表征。
6. Evaluating and Balancing the Risk of Breast Cancer-Specific Death and Other Cause-Specific Death in Elderly Breast Cancer Patients [O] . Yuan Peng, Taobo Hu, Lin Cheng, 2021

机译：在老年乳腺癌患者中评估和平衡乳腺癌特异性死亡和其他原因死亡的风险
7. CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer [O] . Weischer, Maren, Nordestgaard, Børge G., Pharoah, Paul, 2012

机译：患有早期死亡，特定于乳腺癌的死亡以及罹患第二种乳腺癌的风险增加的乳腺癌女性患者的CHEK2 * 1100delC杂合性

CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death Breast Cancer–Specific Death and Increased Risk of a Second Breast Cancer

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