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Impact of CYP2B6 983TC polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

机译：CYP2B6 983T C多态性对HIV感染患者非核苷类逆转录酶抑制剂血浆浓度的影响

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ObjectivesThe aim of this study was to investigate the frequency of CYP2B6 polymorphisms (according to ethnicity) and the influence of heterozygosity and homozygosity on plasma concentrations of efavirenz and nevirapine.

机译：目的本研究的目的是研究CYP2B6基因多态性的频率（根据种族）以及杂合性和纯合性对依非韦伦和奈韦拉平血浆浓度的影响。

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期刊名称 Journal of Antimicrobial Chemotherapy
作者
Christoph Wyen; Heidy Hendra; Martin Vogel; Christian Hoffmann; Heribert Knechten; Norbert H. Brockmeyer; Johannes R. Bogner; Jürgen Rockstroh; Stefan Esser; Hans Jaeger; Thomas Harrer; Stefan Mauss; Jan van Lunzen; Nicole Skoetz; Alexander Jetter; Christiane Groneuer; Gerd Fätkenheuer; Saye H. Khoo; Deirdre Egan; David J. Back; Andrew Owen;
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作者单位

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年(卷),期 -1(61),4
年度 -1
页码 914–918
总页数 8
原文格式 PDF
正文语种
中图分类药学;微生物学;病毒传染病;
关键词
NNRTIs pharmacogenetics pharmacokinetics metabolism drug disposition;

机译：NNRTIs;药物遗传学;药物动力学;代谢;药物处置;

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专利

1. Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients [J] . Christoph Wyen1 Heidy Hendra1 Martin Vogel2 Christian Hoffmann3 Heribert Knechten4 Norbert H. Brockmeyer5 Johannes R. Bogner6 Jürgen Rockstroh2 Stefan Esser7 Hans Jaeger8 Thomas Harrer9 Stefan Mauss10 Jan van Lunzen11 Nicole Skoetz12 Alexander Jetter13 Christiane Groneuer1 Gerd Fätkenheuer1 Saye H. Khoo14 Deirdre Egan14 David J. Back14 and Andrew Owen14 on behalf of the German Competence Network for HIV/AIDS Journal of Antimicrobial Chemotherapy . 2008,第4期

机译：CYP2B6 983T> C多态性对HIV感染患者非核苷类逆转录酶抑制剂血浆浓度的影响
2. Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. [J] . Wyen C, Hendra H, Vogel M, The Journal of Antimicrobial Chemotherapy . 2008,第4期

机译：CYP2B6 983T> C多态性对HIV感染患者非核苷类逆转录酶抑制剂血浆浓度的影响。
3. CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIV-infected patients. [J] . Chen J, Sun J, Ma Q, Therapeutic Drug Monitoring . 2010,第5期

机译：CYP2B6基因多态性和非核苷类逆转录酶抑制剂血浆浓度在中国HIV感染患者中的分布。
4. TREATMENT WITH NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR EFAVIRENZ LEADS TO INCREASE OF CAROTID INTIMA-MEDIA THICKNESS IN MICE [C] . Alexander W Caulk, Rudolph L Gleason Jr. ASME bioengineering conference . 2014

机译：用非核苷逆转录酶抑制剂依法维仑治疗导致小鼠颈动脉内中膜厚度增加
5. Dyslipidemia among HIV-infected tuberculosis patients taking once-daily non-nucleoside reverse transcriptase inhibitor based antiretroviral therapy in India. [D] . Chandrasekaran, Padmapriyadarsini. 2010

机译：在印度，每天接受一次基于非核苷类逆转录酶抑制剂的抗逆转录病毒疗法的HIV感染结核病患者的血脂异常。
6. Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients [O] . Wyen, Christoph, Hendra, Heidy, Vogel, Martin, 2017

机译：CYP2B6 983T> C多态性对HIV感染患者非核苷类逆转录酶抑制剂血浆浓度的影响

Impact of CYP2B6 983TC polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

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