Environmental enrichment reduces adolescent anxiety- and depression-like behaviors of rats subjected to infant nerve injury

摘要

BackgroundInfant nerve injury causes delayed adolescent neuropathic pain, but whether it also leads to psychiatric illness is unknown. Environmental enrichment (EE) increases social communication and activity. Thus, our goal was to test anxiety- and depression-like behaviors after infant peripheral nerve injury and evaluate the effect of environmental enrichment on these models of affective disorders.