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Surgical interventions for high‐grade vulval intraepithelial neoplasia

机译:高级别外阴上皮内瘤变的外科手术干预

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摘要

BackgroundThis is an updated version of an original Cochrane review published in The Cochrane Library, 2011, Issue 1.Vulval intraepithelial neoplasia (VIN) is a pre‐malignant condition of the vulval skin. This uncommon chronic skin condition of the vulva is associated with a high risk of recurrence and the potential to progress to vulval cancer. The condition is complicated by its multicentric and multifocal nature. The incidence of this condition appears to be rising, particularly in the younger age group. There is a lack of consensus on the optimal surgical treatment method. However, the rationale for the surgical treatment of VIN has been to treat the symptoms and exclude any underlying malignancy, with the continued aim of preserving the vulval anatomy and function. Repeated treatments affect local cosmesis and cause psychosexual morbidity, thus impacting the individual's quality of life.
机译:背景这是在Cochrane图书馆,2011年第1期中发表的原始Cochrane综述的更新版本。外阴上皮内瘤变(VIN)是外阴皮肤的恶性前病。外阴的这种罕见的慢性皮肤状况与复发的高风险和发展为外阴癌的可能性有关。该病因其多中心和多焦点性质而变得复杂。这种情况的发生率似乎正在上升,特别是在较年轻的年龄组中。最佳手术治疗方法尚无共识。但是,VIN手术治疗的基本原理是治疗症状并排除任何潜在的恶性肿瘤,其继续目标是保持外阴的解剖结构和功能。重复治疗会影响局部美容,并导致精神病发病,从而影响个人的生活质量。

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