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Accounting for Fairness in a Two-Stage Stochastic Programming Model for Kidney Exchange Programs

机译:肾脏交换程序的两阶段随机编程模型中的公平性说明

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摘要

Kidney exchange programs, which allow a potential living donor whose kidney is incompatible with his or her intended recipient to donate a kidney to another patient in return for a kidney that is compatible for their intended recipient, usually aims to maximize the number of possible kidney exchanges or the total utility of the program. However, the fairness of these exchanges is an issue that has often been ignored. In this paper, as a way to overcome the problems arising in previous studies, we take fairness to be the degree to which individual patient-donor pairs feel satisfied, rather than the extent to which the exchange increases social benefits. A kidney exchange has to occur on the basis of the value of the kidneys themselves because the process is similar to bartering. If the matched kidneys are not of the level expected by the patient-donor pairs involved, the match may break and the kidney exchange transplantation may fail. This study attempts to classify possible scenarios for such failures and incorporate these into a stochastic programming framework. We apply a two-stage stochastic programming method using total utility in the first stage and the sum of the penalties for failure in the second stage when an exceptional event occurs. Computational results are provided to demonstrate the improvement of the proposed model compared to that of previous deterministic models.
机译:肾脏交换计划允许潜在的活体供体的肾脏与他或她的预期接受者不兼容,以将肾脏捐献给另一位患者,以换取与预期接受者兼容的肾脏,这通常旨在最大化可能的肾脏交换次数或该程序的总实用程序。但是,这些交流的公平性是一个经常被忽视的问题。在本文中,作为克服先前研究中出现的问题的一种方法,我们将公平视为患者/供者对个体感到满意的程度,而不是交换增加社会收益的程度。肾脏交换必须根据肾脏本身的价值进行,因为该过程类似于以物易物。如果匹配的肾脏未达到所涉及的患者-供体对预期的水平,则匹配可能会破裂,并且肾脏交换移植可能会失败。本研究试图对此类故障的可能情况进行分类,并将其合并到随机编程框架中。我们采用两阶段随机编程方法,在第一阶段使用总效用,而在第二阶段使用例外事件发生时对失败的惩罚加总。提供计算结果以证明与以前的确定性模型相比,所提出模型的改进。

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