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Comparison between Sandblasted Acid-Etched and Oxidized Titanium Dental Implants: In Vivo Study

机译:喷砂酸蚀和氧化钛牙种植体的比较:体内研究

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摘要

The surface modifications of titanium dental implants play important roles in the enhancement of osseointegration. The objective of the present study was to test two different implant surface treatments on a rabbit model to investigate the osseointegration. The tested surfaces were: a) acid-etched surface with sandblasting treatment (SA) and b) an oxidized implant surface (OS). The roughness was measured by an interferometeric microscope with white light and the residual stress of the surfaces was measured with X-ray residual stress Bragg–Bentano diffraction. Six New Zealand white rabbits were used for the in vivo study. Implants with the two different surfaces (SA and OS) were inserted in the femoral bone. After 12 weeks of implantation, histological and histomorphometric analyses of the blocks containing the implants and the surrounding bone were performed. All the implants were correctly implanted and no signs of infection were observed. SA and OS surfaces were both surrounded by newly formed trabeculae. Histomorphometric analysis revealed that the bone–implant contact % (BIC) was higher around the SA implants (53.49 ± 8.46) than around the OS implants (50.94 ± 16.42), although there were no significant statistical differences among them. Both implant surfaces (SA and OS) demonstrated a good bone response with significant amounts of newly formed bone along the implant surface after 12 weeks of implantation. These results confirmed the importance of the topography and physico–chemical properties of dental implants in the osseointegration.
机译:钛牙科植入物的表面改性在增强骨整合方面起着重要作用。本研究的目的是在兔模型上测试两种不同的植入物表面处理,以研究骨整合。测试的表面为:a)经过喷砂处理的酸蚀表面(SA),以及b)氧化的植入物表面(OS)。用干涉仪显微镜在白光下测量粗糙度,并用X射线残余应力Bragg-Bentano衍射测量表面的残余应力。六只新西兰白兔用于体内研究。将具有两个不同表面(SA和OS)的植入物插入股骨。植入12周后,对包含植入物和周围骨骼的块进行了组织学和组织形态学分析。所有植入物均正确植入,未观察到感染迹象。 SA和OS表面均被新形成的小梁包围。组织形态计量学分析显示,SA植入物周围的骨-植入物接触百分比(BIC)(53.49±8.46)高于OS植入物周围(50.94±16.42),尽管它们之间无显着统计学差异。植入12周后,两个植入物表面(SA和OS)都表现出良好的骨骼反应,并且沿植入物表面出现了大量新形成的骨骼。这些结果证实了牙种植体的地形和理化性质在骨整合中的重要性。

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