SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity

摘要

Aim: (3-methyl-6-chloro-7,8-hydroxy-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine) is an atypical dopamine receptor-1 (D1 receptor) agonist, which exhibits many D1 receptor-independent effects. In the present work, we examined the effects of on monoaminergic transporters in vitro and its anti-depressant activity in vivo.