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Sociometric risk networks and risk for HIV infection.

机译:社会计量风险网络和HIV感染风险。

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摘要

OBJECTIVES: This study examined whether networks of drug-injecting and sexual relationships among drug injectors are associated with individual human immunodeficiency virus (HIV) serostatus and with behavioral likelihood of future infection. METHODS: A cross-sectional survey of 767 drug injectors in New York City was performed with chain-referral and linking procedures to measure large-scale (sociometric) risk networks. Graph-theoretic algebraic techniques were used to detect 92 connected components (drug injectors linked to each other directly or through others) and a 105-member 2-core within a large connected component of 230 members. RESULTS: Drug injectors in the 2-core of the large component were more likely than others to be infected with HIV. Seronegative 2-core members engaged in a wide range of high-risk behaviors, including engaging in risk behaviors with infected drug injectors. CONCLUSIONS: Sociometric risk networks seem to be pathways along which HIV travels in drug-injecting peer groups. The cores of large components can be centers of high-risk behaviors and can become pockets of HIV infection. Preventing HIV from reaching the cores of large components may be crucial in preventing widespread HIV epidemics.
机译:目的:本研究检查了注射毒品网络和注射毒品者之间的性关系是否与个体人类免疫缺陷病毒(HIV)血清状况以及未来感染的行为可能性有关。方法:采用连锁推荐和链接程序对纽约市767个药物注射器进行了横断面调查,以测量大规模(社会计量学)风险网络。使用图论代数技术来检测92个连接的组件(药物注入器直接或通过其他方式彼此链接)和230个成员的大型连接组件中的105个成员的2核。结果:大型部件2芯中的毒品注射者比其他人更容易感染HIV。血清阴性的2核心成员从事各种高风险行为,包括与受感染的药物注射者进行风险行为。结论:社会计量风险网络似乎是艾滋病毒在注射毒品的同伴群体中传播的途径。大组成部分的核心可能是高风险行为的中心,并且可能成为HIV感染的诱因。预防艾滋病毒到达大组成部分的核心对于预防艾滋病毒的广泛流行至关重要。

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