Adverse Prognostic Impact of Bone Marrow Microvessel Density in Multiple Myeloma

机译：骨髓微血管密度对多发性骨髓瘤的不良预后影响

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BackgroundAngiogenesis is important for the proliferation and survival of multiple myeloma (MM) cells. Bone marrow (BM) microvessel density (MVD) is a useful marker of angiogenesis and is determined by immunohistochemical staining with anti-CD34 antibody. This study investigated the prognostic impact of MVD and demonstrated the relationship between MVD and previously mentioned prognostic factors in patients with MM.

机译：背景血管生成对多发性骨髓瘤（MM）细胞的增殖和存活很重要。骨髓（BM）微血管密度（MVD）是有用的血管生成标记，可通过用抗CD34抗体进行免疫组织化学染色来确定。这项研究调查了MVD的预后影响，并证明了MVD与先前提到的MM患者预后因素之间的关系。

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期刊名称 Annals of Laboratory Medicine
作者
Nuri Lee; Hyewon Lee; Soo Young Moon; Ji Yeon Sohn; Sang Mee Hwang; Ok Jin Yoon; Hye Sun Youn; Hyeon-Seok Eom; Sun-Young Kong;
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作者单位

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年(卷),期 2015(35),6
年度 2015
页码 563–569
总页数 7
原文格式 PDF
正文语种
中图分类情报学;
关键词
Multiple myeloma Bone marrow Angiogenesis Microvessel Immunohistochemistry CD34 Progression-free survival;

机译：多发性骨髓瘤;骨髓;血管生成;微血管;免疫组织化学;CD34;无进展生存;

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1. Adverse Prognostic Impact of Bone Marrow Microvessel Density in Multiple Myeloma [J] . Annals of laboratory medicine. . 2015,第6期

机译：骨髓微血管密度对多发性骨髓瘤的不良预后影响
2. Prognostic value of bone marrow microvessel density and angiogenic cytokines in patients with multiple myeloma undergoing autologous stem cell transplant. [J] . Sucak GT, Aki SZ, Yuzbasioglu B, Leukemia and lymphoma . 2011,第7期

机译：骨髓微血管密度和血管生成细胞因子对多发性骨髓瘤患者自体干细胞移植的预后价值。
3. Correlation among DCE-MRI measurements of bone marrow angiogenesis, microvessel density, and extramedullary disease in patients with multiple myeloma [J] . HuangS.-Y., ChenB.-B., LuH.-Y., American Journal of Hematology . 2012,第8期

机译：多发性骨髓瘤患者DCE-MRI测量与骨髓血管生成，微血管密度和髓外疾病之间的相关性
4. Disrupting Physical Interactions Between Multiple Myeloma and the Bone Marrow Niche via Nanoparticle-Mediated RNAi [C] . Michael J. Mitchell, Robert Langer Society for Biomaterials annual meeting and exposition . 2018

机译：通过纳米粒子介导的RNAi破坏多发性骨髓瘤和骨髓生境之间的物理相互作用。
5. Beta-Adrenergic Receptor Mediated Transcriptional Dysregulation in Hematopoietic Stem and Progenitor Cells Leads to Bone Marrow Erythroid Suppression in Multiple Myeloma Patients - ex vivo Investigations [D] . Subramaniam, Vimal. 2021

机译：β-肾上腺素能受体介导的造血干细胞和祖细胞中的转录失调导致多发性骨髓瘤患者的骨髓红细胞抑制 - 以外的研究
6. The Local HIF-2α/EPO Pathway in the Bone Marrow is Associated with Excessive Erythrocytosis and the Increase in Bone Marrow Microvessel Density in Chronic Mountain Sickness [O] . Juan Su, Zhanquan Li, Sen Cui, -1

机译：骨髓中的局部HIF-2α/ EPO途径与过度红细胞增多和慢性高山病患者骨髓微血管密度的增加有关
7. Correlation among DCE-MRI measurements of bone marrow angiogenesis, microvessel density, and extramedullary disease in patients with multiple myeloma [O] . Shang-Yi Huang, Bang-Bin Chen, Hsiao-Yun Lu, 2012

机译：多发性骨髓瘤患者骨髓血管生成，微血管密度和髓外疾病中DCE-MRI测量的相关性

Adverse Prognostic Impact of Bone Marrow Microvessel Density in Multiple Myeloma

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