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Duration of symptoms and spread of colorectal cancer: a short history does not mean early disease.

机译:症状持续时间和结直肠癌扩散:病史短并不意味着早期疾病。

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摘要

The 5-year survival rates for colorectal cancer are generally lower in the UK than other European countries. In an attempt to improve prognosis, central government has stipulated that patients with suspicious symptoms ought to be seen within 2 weeks of referral from a primary care physician. In order to evaluate whether symptom duration affects stage at presentation of colorectal cancer, a retrospective analysis of all patients presenting over a 2-year period to a large district general hospital was performed. There was no significant difference (P = 0.885) in Dukes' staging in patients with symptoms lasting less or more than 6 months. Though seeing patients with symptoms suspicious of colorectal cancer in specialist out-patient clinics within 2 weeks of presentation to the primary care physician would probably reduce the number of patients presenting as an emergency, it is unlikely to improve prognosis. Thus funds diverted towards the 2-week wait are probably best utilised for other procedures such as colonoscopy and for improving care once the diagnosis of cancer has been made. Diagnosis of colorectal cancer at an earlier stage is best achieved by screening of the population.
机译:在英国,大肠癌的5年生存率通常低于其他欧洲国家。为了改善预后,中央政府规定应在转诊初级保健医生的两周内看到可疑症状患者。为了评估症状持续时间是否影响大肠癌患者的分期,对在一家大型综合医院就诊的两年以上所有患者进行了回顾性分析。症状持续时间少于或超过6个月的患者的Dukes分期没有显着差异(P = 0.885)。尽管在就诊给初级保健医生的两周内在专业的门诊诊所就诊可疑结直肠癌的患者可能会减少急诊患者的数量,但不可能改善预后。因此,用于2周等待的资金可能最好用于其他程序,例如结肠镜检查,并在诊断出癌症后用于改善护理。通过筛查人群可以最好地实现大肠癌的早期诊断。

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