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A comparative audit of prevalent incident and interval cancers in the Avon breast screening programme.

机译:在雅芳乳腺癌筛查计划中对流行意外和间歇性癌症进行比较审核。

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摘要

The 4th year of the Avon breast screening programme comprises two distinct groups: those called for screening for the first time (prevalent group) and those who were initially screened 3 years earlier (incident group). The cancer detection rate, stage of disease and rate of interval cancers in these patients have been compared. For the prevalent groups of year 1 and year 4 there was no statistically significant difference in the cancer detection rate, proportion of small tumours or node positivity. For the prevalent and incident groups of year 4, there was no statistically significant difference in the cancer detection rate or proportion of small tumours. There were significantly fewer node-positive tumours in the incident group (5/45 vs 8/23; P < 0.05). Fifty-six interval cancers presented in the 3-year period between years 1 and 4 of screening; 28 (50%) after 24 months. The screening programme may result in tumours being detected at an earlier stage, but this may be offset by the high rate of interval cancers. This suggests that the time between screens may need to be reduced to 2 years.
机译:Avon乳房筛查计划的第4年包括两个不同的组:第一次进行筛查的人群(普遍组)和最初3年前进行筛查的人群(事件组)。比较了这些患者的癌症检出率,疾病分期和间隔癌的发生率。对于第一年和第四年的流行组,癌症检出率,小肿瘤比例或淋巴结阳性率无统计学差异。对于第4年的流行和事件组,癌症检出率或小肿瘤比例没有统计学上的显着差异。在事件组中,淋巴结阳性肿瘤明显更少(5/45比8/23; P <0.05)。在筛查的第1年至第4年的3年期间内出现了56例间发性癌症; 24个月后达到28(50%)。筛查程序可能会导致在较早阶段检测到肿瘤,但这可能会被间隔癌的高发生率所抵消。这表明屏幕之间的时间可能需要减少到2年。

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