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Surgical management of thoracic malignancy in childhood: eight years experience in Leeds.

机译:儿童期胸腔恶性肿瘤的外科治疗:在利兹八年的经验。

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摘要

During the period 1978 to 1986, 13 children aged 2-15 years underwent surgical resection of malignant thoracic tumours. Five children with neuroblastomas presented with chest pain and infections, pleural effusions, dysphagia, lymphadenopathy and paraplegia. Chemo- and radiotherapy were given preoperatively to previously diagnosed cases and postoperatively to all survivors. At operation, complete tumour clearance was possible in only two cases. Two children remain alive with no sign of recurrence at 6 and 7 1/2 years. Eight children with pulmonary metastases had undergone resection of the primary tumour and systemic chemotherapy. All were asymptomatic and were detected by chest radiographs. Wedge resection or lobectomy was performed. Two required contralateral resections at 4 months. Two children remain alive with no evidence of recurrence at 2 and 6 1/2 years. We conclude that aggressive surgical resection of childhood thoracic malignancy is worthwhile, but cooperation with a paediatric oncology team is essential.
机译:在1978年至1986年期间,有13名2-15岁的儿童接受了手术切除恶性胸腔肿瘤。五个神经母细胞瘤患儿表现出胸痛和感染,胸腔积液,吞咽困难,淋巴结肿大和截瘫。术前对先前确诊的病例进行化学疗法和放疗,术后对所有幸存者进行化学疗法和放射疗法。在手术中,只有两种情况可以完全清除肿瘤。两个孩子还活着,在6岁和7 1/2岁时没有复发的迹象。八名肺转移患儿接受了原发肿瘤切除和全身化疗。所有患者均无症状,并经胸部X光片检查。进行楔形切除或肺叶切除术。在4个月时需要进行两次对侧切除。两个孩子还活着,在2岁和6 1/2岁时没有复发的迹象。我们得出结论,儿童胸腔恶性肿瘤的积极手术切除是值得的,但与儿科肿瘤学团队的合作至关重要。

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