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Comparison of Mid-Term Graft Patency between On-Pump and Off-Pump Coronary Artery Bypass Grafting

机译:体外循环和非体外循环冠状动脉旁路移植术中期移植开放性的比较

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摘要

Background: Multiple studies have compared on-pump coronary artery bypass (ONCAB) grafting with off-pump coronary artery bypass (OPCAB) grafting, but the optimal surgical strategy has yet to be established. Furthermore, there is limited evidence regarding mid-term graft patency rates.Methods: Between April 2001 and March 2014, 365 consecutive patients underwent isolated coronary artery bypass grafting (CABG; male: 75%; mean age: 69 ± 10 years). After propensity-score-matched analysis, we assessed the results of 67 patients in each group (ONCAB: group A, OPCAB: group B). The mean follow-up period of graft patency and survival rate was 35 ± 37 months and 54 ± 47 months, respectively.Results: There were no significant differences in baseline characteristics between the two groups. There was a trend for an increased number of distal anastomoses in group B as compared to group A (group A vs. group B: 3.8 ± 1.1 vs. 4.1 ± 1.6, P = 0.17). The total graft patency rate was tend to be lower in group A, but not statistically significant (group A: 156 months, 45.2%; group B: 96 months, 72.6%; P = 0.21). There was no difference for survival and major-adverse-cardiac-and-cerebrovascular-events (MACCE) free rate (P = 0.42 and 0.76, respectively).Conclusion: Propensity-score-matched analysis revealed no difference in mid-term survival rate, MACCE free rate, graft patency rates, and number of distal anastomoses between ONCAB and OPCAB groups.
机译:背景:多项研究已将非体外循环冠状动脉搭桥术(OPCAB)移植与非体外循环冠状动脉搭桥术(ONCAB)进行了比较,但最佳手术策略尚未确立。此外,关于中期移植物通畅率的证据有限。方法:2001年4月至2014年3月,连续365例患者接受了单独的冠状动脉搭桥术(CABG;男性:75%;平均年龄:69±10岁)。经过倾向评分匹配分析后,我们评估了每组67例患者的结果(ONCAB:A组,OPCAB:B组)。结果:两组患者的基线特征无明显差异。平均随访时间为35±37个月和54±47个月。与A组相比,B组远端吻合术的数量有增加的趋势(A组vs B组:3.8±1.1 vs. 4.1±1.6,P = 0.17)。 A组的总移植通畅率趋于降低,但无统计学意义(A组:156个月,45.2%; B组:96个月,72.6%; P = 0.21)。生存率和主要不良心脑血管事件(MACCE)游离率无差异(分别为P = 0.42和0.76)。结论:倾向评分匹配分析显示中期生存率无差异,MACCE游离率,移植物通畅率以及ONCAB和OPCAB组之间远端吻合的数量。

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