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A Phase 1 Randomized Double-Blind Placebo-Controlled Single-Ascending-Dose Study To Investigate the Safety Tolerability and Pharmacokinetics of an Anti-Influenza B Virus Monoclonal Antibody MHAB5553A in Healthy Volunteers

机译：一项1期随机双盲安慰剂对照单剂量研究用于研究健康志愿者中抗B型流感病毒单克隆抗体MHAB5553A的安全性耐受性和药代动力学

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期刊名称 Antimicrobial Agents and Chemotherapy
作者
Jeremy J. Lim; Michael A. Derby; Yaping Zhang; Rong Deng; Richard Larouche; Malia Anderson; Mauricio Maia; Stéphanie Carrier; Isabelle Pelletier; Johanne Girard; Priya Kulkarni; Elizabeth Newton; Jorge A. Tavel;
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作者单位

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年(卷),期 2017(61),8
年度 2017
页码 e00279-17
总页数 10
原文格式 PDF
正文语种
中图分类药学;微生物学;
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专利

1. A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza B Virus Monoclonal Antibody, MHAB5553A, in Healthy Volunteers [J] . Lim Jeremy J., Derby Michael A., Zhang Yaping, Antimicrobial agents and chemotherapy. . 2017,第8期

机译：1阶段，随机，双盲，安慰剂控制的单一上升剂量研究，以研究抗流感B病毒单克隆抗体MHAB5553A，健康志愿者的安全性，耐受性和药代动力学
2. Two Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Studies To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody, MHAA4549A, in Healthy Volunteers [J] . Lim Jeremy J., Deng Rong, Derby Michael A., Antimicrobial agents and chemotherapy. . 2016,第9期

机译：两阶段1，随机，双盲，安慰剂控制，单一升序研究，探讨了抗流感病毒单克隆抗体，MHAA4549a，健康志愿者的安全性，耐受性和药代动力学
3. Two Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Studies To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody, MHAA4549A, in Healthy Volunteers [J] . Lim Jeremy J., Deng Rong, Derby Michael A., Antimicrobial agents and chemotherapy. . 2016,第9期

机译：两个阶段1，随机，双盲，安慰剂对照，单剂量研究，用于研究健康志愿者中抗A型流感病毒单克隆抗体MHAA4549A的安全性，耐受性和药代动力学
4. Pharmacokinetics and Tolerability of Sublingual Fentanyl in Healthy Japanese and Caucasian Volunteers: Phase I, Open-Label Single-Dose Study [C] . U. Lorch, F. Farrell, J. Kilborn, International Pain Clinic Congress . 2008

机译：健康日本和白种人志愿者舌下芬太尼的药代动力学和耐受性：I期，开放标签单剂量研究
5. Two Phase 1 Randomized Double-Blind Placebo-Controlled Single-Ascending-Dose Studies To Investigate the Safety Tolerability and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody MHAA4549A in Healthy Volunteers [O] . Jeremy J. Lim, Rong Deng, Michael A. Derby, 2016

机译：两个阶段1随机双盲安慰剂对照单剂量研究用于研究健康志愿者中抗A型流感病毒单克隆抗体MHAA4549A的安全性耐受性和药代动力学
6. A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti- Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers [O] . Melicent Peck, Michael E. Rothenberg, Rong Deng, 2019

机译：阶段1，随机的单个上升剂量研究，以研究DSTA4637S的安全性，耐受性和药代动力学，抗金黄色葡萄球菌Thiomab抗体 - 抗生素缀合物，在健康的志愿者中

A Phase 1 Randomized Double-Blind Placebo-Controlled Single-Ascending-Dose Study To Investigate the Safety Tolerability and Pharmacokinetics of an Anti-Influenza B Virus Monoclonal Antibody MHAB5553A in Healthy Volunteers

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